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1001. Chronic Colonization with Toxigenic Clostridioides difficile Strains Drives Colonic Tumorigenesis in Mice
BACKGROUND: Long-term effects of chronic and/or recurrent C. difficile infections (CDI) are not well understood, and any potential role of CDI in colorectal cancer (CRC) risk is presently unknown. While pursuing efforts to identify novel procarcinogenic microbes, we identified two mucosal slurries f...
Autores principales: | Drewes, Julia L, Chen, Jie, Knippel, Reece, Markham, Nicholas, Domingue, Jada, Chan, June, McMann, Madison, Stevens, Courtney, Tam, Ada J, White, James, Mohammad, Fuad, Wu, Xinqun, Wu, Shaoguang, Simner, Patricia J, Carroll, Karen C, Ding, Hua, Shrubsole, Martha, Housseau, Franck, Lau, Ken, Coffey, Robert, Sears, Cynthia L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644550/ http://dx.doi.org/10.1093/ofid/ofab466.1195 |
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