543. Molnupiravir Maintains Antiviral Activity Against SARS-CoV-2 Variants In Vitro and in Early Clinical Studies

BACKGROUND: Molnupiravir (MOV, MK-4482, EIDD-2801) is an orally administered prodrug of N-hydroxycytidine (NHC, EIDD-1931), a nucleoside with broad antiviral activity against a range of RNA viruses. MOV acts by driving viral error catastrophe following its incorporation by the viral RdRp into the vi...

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Detalles Bibliográficos
Autores principales: Grobler, Jay, Strizki, Julie, Murgolo, Nicholas, Gao, Wei, Cao, Youfang, Zhang, Ying, Du, Jiejun, Nair, Manoj, Huang, Yaoxing, Luo, Yang, Hazuda, Daria, Ho, David D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Poster Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644651/
http://dx.doi.org/10.1093/ofid/ofab466.742

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