Cargando…
1040. Knee Explant Analysis (KnEA) Using PLG0206 in Periprosthetic Joint Infection (KnEA Study)
BACKGROUND: PLG0206 is a novel engineered cationic antimicrobial peptide being evaluated for treatment of prosthetic joint infections (PJI). This study evaluated the rapid bactericidal activity of PLG0206 to decrease biofilm and planktonic bacteria on ex vivo infected prosthesis following removal fr...
Autores principales: | Huang, David, Parker, Dana, Pachuda, Nicholas, Dobbins, Despina, Steckbeck, Jonathan, Urish, Kenneth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644739/ http://dx.doi.org/10.1093/ofid/ofab466.1234 |
Ejemplares similares
-
Prospective Activity of PLG0206, an Engineered Antimicrobial Peptide, on Chronic Periprosthetic Joint Infection Total Knee Arthroplasty Components Ex Vivo: The Knee Explant Analysis (KnEA) Study
por: Huang, David, et al.
Publicado: (2021) -
The Engineered Antibiotic Peptide PLG0206 Eliminates Biofilms and Is a Potential Treatment for Periprosthetic Joint Infections
por: Huang, David, et al.
Publicado: (2021) -
Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class
por: Huang, David B., et al.
Publicado: (2022) -
1070. In vitro Activity of PLG0206 Against Isolates Commonly Found in Periprosthetic Joint Infections (PJI)
por: Huang, David, et al.
Publicado: (2021) -
1098. A Phase 1 Safety and Tolerability of Single Ascending Doses of a Novel Engineered Cationic Peptide, PLG0206, in Healthy Subjects
por: Huang, David, et al.
Publicado: (2021)