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1052. Characterisation of the DNA binding properties of ridinilazole, a selective antibiotic currently in phase III trials for the treatment of Clostridioides difficile
BACKGROUND: Clostridioides difficile infection (CDI) is recognised by the CDC as an “urgent threat” in the USA, responsible for nearly 13,000 deaths, and carries an economic burden ranging from &5.4 to &6.3 billion per year. In a phase II study, ridinilazole was shown to be effective at trea...
Autores principales: | Mason, Clive, Avis, Tim, Coward, Chris, Powell, David, Duperchy, Esther, Hu, Chenlin, Jahangir Alam, M, Begum, Khurshida, Garey, Kevin W, Reich, Stefanie, Moss, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8644762/ http://dx.doi.org/10.1093/ofid/ofab466.1246 |
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