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Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231

INTRODUCTION: Studies using different assays and technologies showed highly promising diagnostic value of plasma phosphorylated (P-)tau levels for Alzheimer’s disease (AD). We aimed to compare six P-tau Simoa assays, including three P-tau181 (Eli Lilly, ADx, Quanterix), one P-tau217 (Eli Lilly), and...

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Detalles Bibliográficos
Autores principales: Bayoumy, Sherif, Verberk, Inge M. W., den Dulk, Ben, Hussainali, Zulaiga, Zwan, Marissa, van der Flier, Wiesje M., Ashton, Nicholas J., Zetterberg, Henrik, Blennow, Kaj, Vanbrabant, Jeroen, Stoops, Erik, Vanmechelen, Eugeen, Dage, Jeffrey L., Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645090/
https://www.ncbi.nlm.nih.gov/pubmed/34863295
http://dx.doi.org/10.1186/s13195-021-00939-9