Cargando…

‘It is good to have a target in mind’: qualitative views of patients and parents informing a treat to target clinical trial in juvenile-onset systemic lupus erythematosus

OBJECTIVE: We sought to explore patient and parental views on treatment targets, outcome measures and study designs being considered for a future JSLE treat-to-target (T2T) study. METHODS: We conducted topic-guided, semistructured interviews with JSLE patients and parents and analysed the audio reco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Eve M D, Gorst, Sarah L, Al-Abadi, Eslam, Hawley, Daniel P, Leone, Valentina, Pilkington, Clarissa, Ramanan, Athimalaipet V, Rangaraj, Satyapal, Sridhar, Arani, Beresford, Michael W, Young, Bridget
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645274/ https://www.ncbi.nlm.nih.gov/pubmed/33629109 http://dx.doi.org/10.1093/rheumatology/keab173

Ejemplares similares

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study
por: Giani, Teresa, et al.
Publicado: (2021)

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK
por: Massias, Joseph S, et al.
Publicado: (2021)

Attainment of low disease activity and remission targets reduces the risk of severe flare and new damage in childhood lupus
por: Smith, Eve M D, et al.
Publicado: (2021)

Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE
por: Charras, Amandine, et al.
Publicado: (2022)

Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?—observations from the UK JSLE Cohort Study
por: Smith, Eve M D, et al.
Publicado: (2021)

Clinical and laboratory characteristics in juvenile-onset systemic lupus erythematosus across age groups
por: Massias, J S, et al.
Publicado: (2020)

Juvenile Idiopathic Arthritis Associated Uveitis
por: Carlsson, Emil, et al.
Publicado: (2021)

The prevention and treatment of glucocorticoid-induced osteopaenia in juvenile rheumatic disease: A randomised double-blind controlled trial()
por: Rooney, Madeleine, et al.
Publicado: (2019)

Multi-centre national audit of juvenile localised scleroderma: describing current UK practice in disease assessment and management
por: Lythgoe, Hanna, et al.
Publicado: (2018)

Retrospective audit of access to care for children and young people diagnosed with localised scleroderma or juvenile systemic sclerosis in the United Kingdom
por: Hawley, Daniel P, et al.
Publicado: (2012)

Juvenile idiopathic arthritis-associated uveitis
por: Clarke, Sarah L. N., et al.
Publicado: (2016)

O07 Managing relapsing and refractory lupus nephritis in juvenile systemic lupus erythematosus: a case report
por: Javed, Farhan, et al.
Publicado: (2021)

Treat to Target (Drug-Free) Inactive Disease in JIA: To What Extent Is This Possible?
por: Ramanan, Athimalaipet V., et al.
Publicado: (2022)

Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an international task force
por: Smith, Eve Mary Dorothy, et al.
Publicado: (2023)

Onset of juvenile dermatomyositis following varicella infection in a 12-month-old child: a case report
por: McCrea, Nadine, et al.
Publicado: (2014)

Protective parents and permissive children: what qualitative interviews with parents and children can tell us about the feasibility of juvenile idiopathic arthritis trials
por: Sherratt, Frances C., et al.
Publicado: (2018)

Vasculitis in Juvenile-Onset Systemic Lupus Erythematosus
por: Smith, Eve M. D., et al.
Publicado: (2019)

Maternal microchimerism in muscle biopsies from children with juvenile dermatomyositis
por: Ye, Yi, et al.
Publicado: (2012)

Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis
por: Donn, Rachelle, et al.
Publicado: (2008)

Same but different? A thematic analysis on adalimumab biosimilar switching among patients with juvenile idiopathic arthritis
por: Renton, William D., et al.
Publicado: (2019)

Platelet Glycoprotein Ib α‐Chain as a Putative Therapeutic Target for Juvenile Idiopathic Arthritis: A Mendelian Randomization Study
por: Luo, Shan, et al.
Publicado: (2021)

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature
por: Chiewchengchol, Direkrit, et al.
Publicado: (2015)

Towards molecular-pathology informed clinical trials in childhood arthritis to achieve precision medicine in juvenile idiopathic arthritis
por: Wedderburn, Lucy R, et al.
Publicado: (2023)

Discontinuing adalimumab in patients with controlled juvenile idiopathic arthritis-associated uveitis (ADJUST—Adalimumab in Juvenile Idiopathic Arthritis-associated Uveitis Stopping Trial): study protocol for a randomised controlled trial
por: Acharya, Nisha R., et al.
Publicado: (2020)

The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus
por: Ballantine, Lucy E, et al.
Publicado: (2014)

Targeting hyperinflammation in infection: can we harness the COVID-19 therapeutics momentum to end the dengue drugs drought?
por: McBride, Angela, et al.
Publicado: (2021)

Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial
por: Ramanan, Athimalaipet V, et al.
Publicado: (2020)

The effect of juvenile systemic lupus erythematosus serum activated macrophages on a lupus nephritis model
por: Vernon, April S, et al.
Publicado: (2014)

O23 Pulmonary emboli in a teenager with GPA: management dilemmas
por: Deepak, Sam, et al.
Publicado: (2020)

Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature
por: Rodsaward, Pongsawat, et al.
Publicado: (2017)

Examining Health Outcomes in Juvenile Idiopathic Arthritis: A Genetic Epidemiology Study
por: Clarke, Sarah L. N., et al.
Publicado: (2022)

A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)
por: Ramanan, Athimalaipet V, et al.
Publicado: (2014)

Acute longitudinal myelitis as the first presentation in child with systemic lupus erythematosus
por: Shivamurthy, Vinay M., et al.
Publicado: (2013)

“Environmental risk factors associated with juvenile idiopathic arthritis associated uveitis: a systematic review of the literature”
por: Clarke, Sarah L. N., et al.
Publicado: (2021)

B cell activating factor in juvenile onset systemic lupus erythematosus, looking beyond the B cell
por: Richards, Ella, et al.
Publicado: (2014)

Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis
por: Hinks, Anne, et al.
Publicado: (2013)

Cross sectional, qualitative thematic analysis of patient perspectives of disease impact in juvenile idiopathic arthritis-associated uveitis
por: Sen, Ethan S., et al.
Publicado: (2017)

Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative
por: Constantin, Tamas, et al.
Publicado: (2018)

Advancing Transition in Resource-Constrained Settings
por: Sinnappurajar, Praisoody, et al.
Publicado: (2022)

Immunoglobulin, glucocorticoid, or combined therapy for multisystem inflammatory syndrome in children
por: Chew, Christine, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cb83iv2r1aj44t8vs9nvj3rdtr