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Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning

We hypothesized that carbon monoxide (CO) establishes an inflammatory cycle mediated by microparticles (MPs). Mice exposed to a CO protocol (1000 ​ppm for 40 ​min and then 3000 ​ppm for 20 ​min) that causes neuroinflammation exhibit NF-κB activation in astrocytes leading to generation of MPs express...

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Detalles Bibliográficos
Autores principales: Ruhela, Deepa, Bhopale, Veena M., Kalakonda, Sudhakar, Thom, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645452/
https://www.ncbi.nlm.nih.gov/pubmed/34917988
http://dx.doi.org/10.1016/j.bbih.2021.100398

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