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Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism
Pendrin is a Cl(−)/HCO(3)(−) exchanger selectively present in the intercalated cells of the kidney. Although experimental studies have demonstrated that pendrin regulates blood pressure downstream of the renin-angiotensin-aldosterone system, its role in human hypertension remains unclear. Here, we a...
Autores principales: | Ochiai-Homma, Fumika, Kuribayashi-Okuma, Emiko, Tsurutani, Yuya, Ishizawa, Kenichi, Fujii, Wataru, Odajima, Kohei, Kawagoe, Mika, Tomomitsu, Yoshihiro, Murakawa, Masataka, Asakawa, Shinichiro, Hirohama, Daigoro, Nagura, Michito, Arai, Shigeyuki, Yamazaki, Osamu, Tamura, Yoshifuru, Fujigaki, Yoshihide, Nishikawa, Tetsuo, Shibata, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645477/ https://www.ncbi.nlm.nih.gov/pubmed/34326480 http://dx.doi.org/10.1038/s41440-021-00710-5 |
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