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Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory

INTRODUCTION: A significant improvement in safety and efficacy of ablation for paroxysmal atrial fibrillation (PAF) has been reported by experienced centers over recent years; however, data from real-life surveys and smaller electrophysiology (EP) laboratories have been less optimistic. AIM: To asse...

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Autores principales: Kulakowski, Piotr, Sikorska, Agnieszka, Piotrowski, Roman, Kryński, Tomasz, Baran, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645536/
https://www.ncbi.nlm.nih.gov/pubmed/33423186
http://dx.doi.org/10.1007/s10840-020-00937-1
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author Kulakowski, Piotr
Sikorska, Agnieszka
Piotrowski, Roman
Kryński, Tomasz
Baran, Jakub
author_facet Kulakowski, Piotr
Sikorska, Agnieszka
Piotrowski, Roman
Kryński, Tomasz
Baran, Jakub
author_sort Kulakowski, Piotr
collection PubMed
description INTRODUCTION: A significant improvement in safety and efficacy of ablation for paroxysmal atrial fibrillation (PAF) has been reported by experienced centers over recent years; however, data from real-life surveys and smaller electrophysiology (EP) laboratories have been less optimistic. AIM: To asses efficacy of ablation for PAF in a middle-volume EP center over last years. METHODS: Retrospective analysis of 1 year efficacy and safety of ablation for PAF in three cohorts of patients treated between 2011 and 2014 (period I), 2015–2017 (period II), and 2018–2019 (period III). RESULTS: Of 234 patients (mean age 57 ± 9 years, 165 males), 81 (35%) were treated in period I, 84 (36%) in period II, and 69 (29%) in period III. The overall efficacy of ablation during all analyzed periods was 67%. The overall efficacy of ablation increased over time—from 56% in period I to 68% in period II and 81% in period III. Significant improvement was achieved using radiofrequency ablation (RF) (53% in period I vs 82% in period III, and 55% in period II vs 82% in period III, p = 0.003 and 0.0012, respectively) whereas positive trend in the improvement of cryoballoon efficacy was NS. The rate of peri-procedural complications was 9% and it did not change significantly over time. CONCLUSIONS: This real-life observational study from a medium volume EP center shows that progress in PAF ablation, especially RF, reported by highly-skilled centers, can be reproduced in real life by less experienced operators.
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spelling pubmed-86455362021-12-17 Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory Kulakowski, Piotr Sikorska, Agnieszka Piotrowski, Roman Kryński, Tomasz Baran, Jakub J Interv Card Electrophysiol Article INTRODUCTION: A significant improvement in safety and efficacy of ablation for paroxysmal atrial fibrillation (PAF) has been reported by experienced centers over recent years; however, data from real-life surveys and smaller electrophysiology (EP) laboratories have been less optimistic. AIM: To asses efficacy of ablation for PAF in a middle-volume EP center over last years. METHODS: Retrospective analysis of 1 year efficacy and safety of ablation for PAF in three cohorts of patients treated between 2011 and 2014 (period I), 2015–2017 (period II), and 2018–2019 (period III). RESULTS: Of 234 patients (mean age 57 ± 9 years, 165 males), 81 (35%) were treated in period I, 84 (36%) in period II, and 69 (29%) in period III. The overall efficacy of ablation during all analyzed periods was 67%. The overall efficacy of ablation increased over time—from 56% in period I to 68% in period II and 81% in period III. Significant improvement was achieved using radiofrequency ablation (RF) (53% in period I vs 82% in period III, and 55% in period II vs 82% in period III, p = 0.003 and 0.0012, respectively) whereas positive trend in the improvement of cryoballoon efficacy was NS. The rate of peri-procedural complications was 9% and it did not change significantly over time. CONCLUSIONS: This real-life observational study from a medium volume EP center shows that progress in PAF ablation, especially RF, reported by highly-skilled centers, can be reproduced in real life by less experienced operators. Springer US 2021-01-09 2021 /pmc/articles/PMC8645536/ /pubmed/33423186 http://dx.doi.org/10.1007/s10840-020-00937-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kulakowski, Piotr
Sikorska, Agnieszka
Piotrowski, Roman
Kryński, Tomasz
Baran, Jakub
Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title_full Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title_fullStr Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title_full_unstemmed Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title_short Ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
title_sort ablation for paroxysmal atrial fibrillation—real-life results from a middle-volume electrophysiology laboratory
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645536/
https://www.ncbi.nlm.nih.gov/pubmed/33423186
http://dx.doi.org/10.1007/s10840-020-00937-1
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