Cargando…

Exposure of Microglia to Interleukin-4 Represses NF-κB-Dependent Transcription of Toll-Like Receptor-Induced Cytokines

Interleukin (IL)-4 is a cytokine that affects both adaptive and innate immune responses. In the central nervous system, microglia express IL-4 receptors and it has been described that IL-4-exposed microglia acquire anti-inflammatory properties. We here demonstrate that IL-4 exposure induces changes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuiderwijk-Sick, Ella A., van der Putten, Céline, Timmerman, Raissa, Veth, Jennifer, Pasini, Erica M., van Straalen, Linda, van der Valk, Paul, Amor, Sandra, Bajramovic, Jeffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645606/ https://www.ncbi.nlm.nih.gov/pubmed/34880868 http://dx.doi.org/10.3389/fimmu.2021.771453

Ejemplares similares

P2Y6 receptor-mediated signaling amplifies TLR-induced pro-inflammatory responses in microglia
por: Timmerman, Raissa, et al.
Publicado: (2022)

In silico-in vitro modeling to uncover cues involved in establishing microglia identity: TGF-β3 and laminin can drive microglia signature gene expression
por: Timmerman, Raissa, et al.
Publicado: (2023)

Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself
por: Burm, Saskia Maria, et al.
Publicado: (2016)

An Overview of in vitro Methods to Study Microglia
por: Timmerman, Raissa, et al.
Publicado: (2018)

In vitro microglia models: the era of engineered cell microenvironments
por: Sharaf, Ahmed, et al.
Publicado: (2023)

Two-Photon Polymerization of 2.5D and 3D Microstructures Fostering a Ramified Resting Phenotype in Primary Microglia
por: Sharaf, Ahmed, et al.
Publicado: (2022)

Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program
por: Dubbelaar, M.L., et al.
Publicado: (2021)

Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain
por: Nutma, Erik, et al.
Publicado: (2021)

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
por: van Horssen, Jack, et al.
Publicado: (2012)

Interleukin-7 and Toll-Like Receptor 7 Induce Synergistic B Cell and T Cell Activation
por: Bikker, Angela, et al.
Publicado: (2014)

Regulatory T Cells in Development and Prediction of Necrotizing Enterocolitis in Preterm Neonates: A Scoping Review
por: Zuiderwijk, Mara O., et al.
Publicado: (2022)

Isocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas: Indication of a significant role of microglia/macrophages in glial tumorigenesis
por: Zheng, Ping-Pin, et al.
Publicado: (2012)

Repression of telomere-associated genes by microglia activation in neuropsychiatric disease
por: Kronenberg, Golo, et al.
Publicado: (2016)

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain
por: Minderman, Marthe, et al.
Publicado: (2023)

Management of mild hidradenitis suppurativa: our greatest challenge yet
por: van der Zee, H.H., et al.
Publicado: (2021)

Interleukin-33 regulates the functional state of microglia
por: Xiong, Tianqing, et al.
Publicado: (2022)

Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis
por: He, Lei, et al.
Publicado: (2011)

Lobular panniculitis after subcutaneous administration of interleukin-2 (IL-2), and its exacerbation during intravenous therapy with IL-2.
por: Baars, J. W., et al.
Publicado: (1992)

Tumor-Associated Microglia and Macrophages in the Glioblastoma Microenvironment and Their Implications for Therapy
por: Andersen, Rikke Sick, et al.
Publicado: (2021)

Toll-Like Receptors 2, -3 and -4 Prime Microglia but not Astrocytes Across Central Nervous System Regions for ATP-Dependent Interleukin-1β Release
por: Facci, Laura, et al.
Publicado: (2014)

Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes
por: Marinelli, Carla, et al.
Publicado: (2015)

Microglia Activation in Retinal Ischemia Triggers Cytokine and Toll-Like Receptor Response
por: Wagner, Natalie, et al.
Publicado: (2020)

The Effect of C-Phycocyanin on Microglia Activation Is Mediated by Toll-like Receptor 4
por: Piovan, Anna, et al.
Publicado: (2022)

Neuronal Synapse Formation Induced by Microglia and Interleukin 10
por: Lim, So-Hee, et al.
Publicado: (2013)

Microglia and CNS Interleukin-1: Beyond Immunological Concepts
por: Liu, Xiaoyu, et al.
Publicado: (2018)

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons
por: Singh, Shailender, et al.
Publicado: (2013)

Quality assurance in postgraduate pathology training the Dutch way: regular assessment, monitoring of training programs but no end of training examination
por: van der Valk, Paul
Publicado: (2016)

Reptile Toll-like receptor 5 unveils adaptive evolution of bacterial flagellin recognition
por: Voogdt, Carlos G. P., et al.
Publicado: (2016)

The Role of Interleukin-4 and Interleukin-10 in Osteoarthritic Joint Disease: A Systematic Narrative Review
por: van Helvoort, E.M., et al.
Publicado: (2022)

Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals
por: Mylona, Eleni E, et al.
Publicado: (2012)

Toll like receptor 1 polymorphisms and susceptibility to invasive candidiasis
por: Plantinga, T, et al.
Publicado: (2009)

Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
por: Gurley, Catherine, et al.
Publicado: (2008)

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
por: Fellner, Lisa, et al.
Publicado: (2013)

Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal injury
por: Ifuku, Masataka, et al.
Publicado: (2020)

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus
por: van der Sluijs, Koenraad F., et al.
Publicado: (2003)

Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures
por: Sun, Yi, et al.
Publicado: (2019)

Moving towards zero new HIV infections: The importance of combination prevention
por: van Sighem, Ard, et al.
Publicado: (2022)

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases
por: Borggrewe, Malte, et al.
Publicado: (2018)

Interleukin 1 of the central nervous system is produced by ameboid microglia
Publicado: (1986)

Interleukin 13 on Microglia is Neurotoxic in Lipopolysaccharide-injected Striatum in vivo
por: Hong, Ah Reum, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7fknqbam9flbhdabt5vjgpracc