Cargando…
Safety and efficacy of depatuxizumab mafodotin in Japanese patients with malignant glioma: A nonrandomized, phase 1/2 trial
INTELLANCE‐J was a phase 1/2 study of a potent antibody‐drug conjugate targeting epidermal growth factor receptor (EGFR), depatuxizumab mafodotin (Depatux‐M), as a second‐ or first‐line therapy, alone or combined with chemotherapy or chemoradiotherapy in 53 Japanese patients with World Health Organi...
Autores principales: | Narita, Yoshitaka, Muragaki, Yoshihiro, Kagawa, Naoki, Asai, Katsunori, Nagane, Motoo, Matsuda, Masahide, Ueki, Keisuke, Kuroda, Junichiro, Date, Isao, Kobayashi, Hiroyuki, Kumabe, Toshihiro, Beppu, Takaaki, Kanamori, Masayuki, Kasai, Shota, Nishimura, Yasuko, Xiong, Hao, Ocampo, Christopher, Yamada, Masakazu, Mishima, Kazuhiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645742/ https://www.ncbi.nlm.nih.gov/pubmed/34609773 http://dx.doi.org/10.1111/cas.15153 |
Ejemplares similares
-
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial
por: Lassman, Andrew B, et al.
Publicado: (2022) -
Efficacy and safety results of depatuxizumab mafodotin (ABT‐414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor
por: Goss, Glenwood D., et al.
Publicado: (2018) -
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial
por: Lassman, Andrew B, et al.
Publicado: (2019) -
Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study
por: van den Bent, Martin, et al.
Publicado: (2017) -
A Phase 3b Study for Management of Ocular Side Effects in Patients with Epidermal Growth Factor Receptor-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin
por: Vize, Colin J., et al.
Publicado: (2023)