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Programmed death (PD)‐1/PD‐ligand 1 blockade mediates antiangiogenic effects by tumor‐derived CXCL10/11 as a potential predictive biomarker

Immune checkpoint inhibitor (ICI) programmed death (PD)‐1/PD‐ligand 1 (PD‐L1) blockade has been approved for various cancers. However, the underlying antitumor mechanisms mediated by ICIs and the predictive biomarkers remain unclear. We report the effects of anti‐PD‐L1/PD‐1 Ab in tumor angiogenesis....

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Detalles Bibliográficos
Autores principales: Mitsuhashi, Atsushi, Kondoh, Kensuke, Horikawa, Kazuki, Koyama, Kazuya, Nguyen, Na Thi, Afroj, Tania, Yoneda, Hiroto, Otsuka, Kenji, Ogino, Hirokazu, Nokihara, Hiroshi, Shinohara, Tsutomu, Nishioka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645761/
https://www.ncbi.nlm.nih.gov/pubmed/34628702
http://dx.doi.org/10.1111/cas.15161