Cargando…

SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2

Pancreatic cancer has an extremely poor prognosis because of its resistance to conventional therapies. Cancer stem cell (CSC)‐targeted therapy is considered a promising approach for this disease. Epithelial‐mesenchymal transition‐inducing transcription factors (EMT‐TFs) contribute to CSC properties...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masuo, Kenji, Chen, Ru, Yogo, Akitada, Sugiyama, Aiko, Fukuda, Akihisa, Masui, Toshihiko, Uemoto, Shinji, Seno, Hiroshi, Takaishi, Shigeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645768/ https://www.ncbi.nlm.nih.gov/pubmed/34628696 http://dx.doi.org/10.1111/cas.15162

Ejemplares similares

Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer
por: Watanabe, Sadanori, et al.
Publicado: (2022)

Inhibition of dopamine receptor D1 signaling promotes human bile duct cancer progression via WNT signaling
por: Yogo, Akitada, et al.
Publicado: (2022)

Time–frequency analysis of serum with proton nuclear magnetic resonance for diagnosis of pancreatic cancer
por: Sato, Asahi, et al.
Publicado: (2020)

Promoter-Level Transcriptome Identifies Stemness Associated With Relatively High Proliferation in Pancreatic Cancer Cells
por: Chen, Ru, et al.
Publicado: (2020)

Safety and efficacy of neoadjuvant chemoradiotherapy with moderately hypofractionated intensity‐modulated radiotherapy for resectable pancreatic cancer: A prospective, open‐label, phase II study
por: Masui, Toshihiko, et al.
Publicado: (2023)

Snail depletes the tumorigenic potential of glioblastoma
por: Savary, K, et al.
Publicado: (2013)

Impact of neoadjuvant intensity-modulated radiation therapy on borderline resectable pancreatic cancer with arterial abutment; a prospective, open-label, phase II study in a single institution
por: Masui, Toshihiko, et al.
Publicado: (2022)

Current state and future evolution of pancreatic islet transplantation
por: Anazawa, Takayuki, et al.
Publicado: (2018)

Recent epidemiology of patients with gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) in Japan: a population-based study
por: Masui, Toshihiko, et al.
Publicado: (2020)

JNK pathway plays a critical role for expansion of human colorectal cancer in the context of BRG1 suppression
por: Yoshikawa, Takaaki, et al.
Publicado: (2022)

Identification of modules and functional analysis in CRC subtypes by integrated bioinformatics analysis
por: Chen, Ru, et al.
Publicado: (2019)

Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis
por: Guiot, J., et al.
Publicado: (2016)

Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis
por: Hirata, Koji, et al.
Publicado: (2019)

Hepatocellular carcinoma with duodenal invasion resected subsequent to multimodal therapies: A case report
por: Ito, Takashi, et al.
Publicado: (2019)

Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis
por: Masuda, Tomonori, et al.
Publicado: (2023)

Long-term Prognosis and Recurrence of Primary Sclerosing Cholangitis After Liver Transplantation: A Single-Center Experience
por: Ueda, Yoshihide, et al.
Publicado: (2017)

The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system
por: Nagao, Munemasa, et al.
Publicado: (2023)

Increased Concentrations of Insulin-Like Growth Factor Binding Protein (IGFBP)-2, IGFBP-3, and IGFBP-4 Are Associated With Fetal Mortality in Pregnant Cows
por: Mense, Kirsten, et al.
Publicado: (2018)

IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults
por: Pettersson-Pablo, Paul, et al.
Publicado: (2021)

Regulation of IGFBP-2 expression during fasting
por: Kang, Hye Suk, et al.
Publicado: (2015)

A case of successful conversion from everolimus to surgical resection of a giant pancreatic neuroendocrine tumor
por: Sato, Asahi, et al.
Publicado: (2017)

Cholangiocarcinoma after flow diversion surgery for congenital biliary dilatation: A case report and review of literature
por: Ataka, Ryo, et al.
Publicado: (2019)

Prognostic value of metastin expression in human pancreatic cancer
por: Nagai, Kazuyuki, et al.
Publicado: (2009)

Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging
por: Maruno, Takahisa, et al.
Publicado: (2021)

Pro-tumorigenic roles of TGF-β signaling during the early stages of liver tumorigenesis through upregulation of Snail
por: Moon, Hyuk, et al.
Publicado: (2017)

Insulin Growth Factor Binding Protein 7 (IGFBP7)-Related Cancer and IGFBP3 and IGFBP7 Crosstalk
por: Jin, Li, et al.
Publicado: (2020)

Gastric Cancer from a Hyperplastic Polyp on an Endoscopic Submucosal Dissection Scar
por: Sono, Makoto, et al.
Publicado: (2018)

Paraplegia as an initial manifestation of pancreatic cancer
por: Sono, Makoto, et al.
Publicado: (2019)

IGFBP-2: a critical player in cancer and metabolism
por: Werther, George, et al.
Publicado: (2015)

Serum IGFBP-2 and Risk of Atypical Hyperplasia of the Breast
por: Catsburg, Chelsea, et al.
Publicado: (2015)

IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma
por: Myers, Amy L., et al.
Publicado: (2015)

Potential Functions of IGFBP-2 for Ovarian Folliculogenesis and Steroidogenesis
por: Spitschak, Marion, et al.
Publicado: (2018)

A subcentimeter duodenal neuroendocrine neoplasm with a liver metastasis upgraded to G3: a case report
por: Kitada, Tomoya, et al.
Publicado: (2021)

Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway
por: Liu, Yadong, et al.
Publicado: (2021)

Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
por: Taki, Mana, et al.
Publicado: (2018)

Elevated serum levels of IGFBP-2 found in children suffering from acute leukaemia is accompanied by the occurrence of IGFBP-2 mRNA in the tumour clone.
por: Wex, H., et al.
Publicado: (1998)

Living donor liver transplantation for adult Budd Chiari syndrome – Resection without replacement of retrohepatic IVC: A case report
por: Sabra, Tarek Abdelazeem, et al.
Publicado: (2017)

Tumorigenicity of RTK/RAS in urothelium
por: Wu, Xue-Ru, et al.
Publicado: (2015)

Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis
por: Hoeflich, Andreas, et al.
Publicado: (2021)

Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates
por: Hoeflich, Andreas, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kbbnudvat40mbi6a9m25qof3rj