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Tet2 deficiency in immune cells exacerbates tumor progression by increasing angiogenesis in a lung cancer model
Immune cells harboring somatic mutations reportedly infiltrate cancer tissues in patients with solid cancers and accompanying clonal hematopoiesis. Loss‐of‐function TET2 mutations are frequently observed in clonal hematopoiesis in solid cancers. Here, using a mouse lung cancer model, we evaluated th...
Autores principales: | Nguyen, Yen T. M., Fujisawa, Manabu, Nguyen, Tran B., Suehara, Yasuhito, Sakamoto, Tatsuhiro, Matsuoka, Ryota, Abe, Yoshiaki, Fukumoto, Kota, Hattori, Keiichiro, Noguchi, Masayuki, Matsubara, Daisuke, Chiba, Shigeru, Sakata‐Yanagimoto, Mamiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645781/ https://www.ncbi.nlm.nih.gov/pubmed/34657351 http://dx.doi.org/10.1111/cas.15165 |
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