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Combining inter-observer variability, range and setup uncertainty in a variance-based sensitivity analysis for proton therapy
Margin concepts in proton therapy aim to ensure full dose coverage of the clinical target volume (CTV) in presence of setup and range uncertainty. Due to inter-observer variability (IOV), the CTV itself is uncertain. We present a framework to evaluate the combined impact of IOV, setup and range unce...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645917/ https://www.ncbi.nlm.nih.gov/pubmed/34917780 http://dx.doi.org/10.1016/j.phro.2021.11.005 |