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Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer

Tumour cells modify their cellular metabolism with the aim to sustain uncontrolled proliferation. Cancer cells necessitate adequate amounts of NAD and NADPH to support several enzymes that are usually overexpressed and/or overactivated. Nicotinamide adenine dinucleotide (NAD) is an essential cofacto...

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Detalles Bibliográficos
Autores principales: Colombo, Giorgia, Gelardi, Edoardo Luigi Maria, Balestrero, Federica Carolina, Moro, Marianna, Travelli, Cristina, Genazzani, Armando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645963/
https://www.ncbi.nlm.nih.gov/pubmed/34880756
http://dx.doi.org/10.3389/fphar.2021.758320

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