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Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling

Pseudouridine (Ψ) is an abundant mRNA modification in mammalian transcriptome, but its functions have remained elusive due to the difficulty of transcriptome-wide mapping. We develop a nanopore native RNA sequencing method for quantitative Ψ prediction (NanoPsu) that utilizes native content training...

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Detalles Bibliográficos
Autores principales:	Huang, Sihao, Zhang, Wen, Katanski, Christopher D., Dersh, Devin, Dai, Qing, Lolans, Karen, Yewdell, Jonathan, Eren, A. Murat, Pan, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646010/ https://www.ncbi.nlm.nih.gov/pubmed/34872593 http://dx.doi.org/10.1186/s13059-021-02557-y

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