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Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature

Background: Liver bleeding secondary to haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is uncommon, but a life-threatening peripartum condition that needs a prompt multidisciplinary approach. Case Presentation: In this study, we presented a case of 28-year-old pregnant w...

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Autores principales: Messina, Valentina, Dondossola, Daniele, Paleari, Maria Chiara, Fornoni, Gianluca, Tubiolo, Daniela, Vergani, Patrizia, Rona, Roberto, Rossi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646087/
https://www.ncbi.nlm.nih.gov/pubmed/34881288
http://dx.doi.org/10.3389/fsurg.2021.774702
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author Messina, Valentina
Dondossola, Daniele
Paleari, Maria Chiara
Fornoni, Gianluca
Tubiolo, Daniela
Vergani, Patrizia
Rona, Roberto
Rossi, Giorgio
author_facet Messina, Valentina
Dondossola, Daniele
Paleari, Maria Chiara
Fornoni, Gianluca
Tubiolo, Daniela
Vergani, Patrizia
Rona, Roberto
Rossi, Giorgio
author_sort Messina, Valentina
collection PubMed
description Background: Liver bleeding secondary to haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is uncommon, but a life-threatening peripartum condition that needs a prompt multidisciplinary approach. Case Presentation: In this study, we presented a case of 28-year-old pregnant woman, who was presented to the obstetrics department with signs of preeclampsia and foetal growth restriction. An emergency caesarean section was performed, and the patient developed a HELLP syndrome complicated by spontaneous liver rupture. After radiological and surgical procedures, liver failure became evident and liver transplantation was successfully performed. The patient and her daughter are now alive. Conclusions: Despite the rarity of this disease, liver complications due to HELLP syndrome must be properly diagnosed and treated given the gravity of the possible evolution in young women. After diagnosis, the patients must be treated in specialised centres with gynaecological, liver surgery, and transplant skills.
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spelling pubmed-86460872021-12-07 Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature Messina, Valentina Dondossola, Daniele Paleari, Maria Chiara Fornoni, Gianluca Tubiolo, Daniela Vergani, Patrizia Rona, Roberto Rossi, Giorgio Front Surg Surgery Background: Liver bleeding secondary to haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is uncommon, but a life-threatening peripartum condition that needs a prompt multidisciplinary approach. Case Presentation: In this study, we presented a case of 28-year-old pregnant woman, who was presented to the obstetrics department with signs of preeclampsia and foetal growth restriction. An emergency caesarean section was performed, and the patient developed a HELLP syndrome complicated by spontaneous liver rupture. After radiological and surgical procedures, liver failure became evident and liver transplantation was successfully performed. The patient and her daughter are now alive. Conclusions: Despite the rarity of this disease, liver complications due to HELLP syndrome must be properly diagnosed and treated given the gravity of the possible evolution in young women. After diagnosis, the patients must be treated in specialised centres with gynaecological, liver surgery, and transplant skills. Frontiers Media S.A. 2021-11-22 /pmc/articles/PMC8646087/ /pubmed/34881288 http://dx.doi.org/10.3389/fsurg.2021.774702 Text en Copyright © 2021 Messina, Dondossola, Paleari, Fornoni, Tubiolo, Vergani, Rona and Rossi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Messina, Valentina
Dondossola, Daniele
Paleari, Maria Chiara
Fornoni, Gianluca
Tubiolo, Daniela
Vergani, Patrizia
Rona, Roberto
Rossi, Giorgio
Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title_full Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title_fullStr Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title_full_unstemmed Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title_short Liver Bleeding Due to HELLP Syndrome Treated With Embolization and Liver Transplantation: A Case Report and Review of the Literature
title_sort liver bleeding due to hellp syndrome treated with embolization and liver transplantation: a case report and review of the literature
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646087/
https://www.ncbi.nlm.nih.gov/pubmed/34881288
http://dx.doi.org/10.3389/fsurg.2021.774702
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