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Novel Treatments from Inhibition of the Intestinal Sodium–Hydrogen Exchanger 3

Plasma membrane sodium–hydrogen exchangers (NHE) transport Na(+) into cells in exchange for H(+). While there are nine isoforms of NHE in humans, this review focuses on the NHE3 isoform, which is abundantly expressed in the gastrointestinal tract, where it plays a key role in acid–base balance and w...

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Detalles Bibliográficos
Autores principales: Kovesdy, Csaba P, Adebiyi, Adebowale, Rosenbaum, David, Jacobs, Jeffrey W, Quarles, L Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646223/
https://www.ncbi.nlm.nih.gov/pubmed/34880650
http://dx.doi.org/10.2147/IJNRD.S334024