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Population pharmacokinetic modeling of GS‐441524, the active metabolite of remdesivir, in Japanese COVID‐19 patients with renal dysfunction

Remdesivir, a prodrug of the nucleoside analog GS‐441524, plays a key role in the treatment of coronavirus disease 2019 (COVID‐19). However, owing to limited information on clinical trials and inexperienced clinical use, there is a lack of pharmacokinetic (PK) data in patients with COVID‐19 with spe...

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Detalles Bibliográficos
Autores principales:	Sukeishi, Asami, Itohara, Kotaro, Yonezawa, Atsushi, Sato, Yuki, Matsumura, Katsuyuki, Katada, Yoshiki, Nakagawa, Takayuki, Hamada, Satoshi, Tanabe, Naoya, Imoto, Eishi, Kai, Shinichi, Hirai, Toyohiro, Yanagita, Motoko, Ohtsuru, Shigeru, Terada, Tomohiro, Ito, Isao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646568/ https://www.ncbi.nlm.nih.gov/pubmed/34793625 http://dx.doi.org/10.1002/psp4.12736

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