Cargando…

SARS‐CoV‐2 Alpha, Beta, and Delta variants display enhanced Spike‐mediated syncytia formation

Severe COVID‐19 is characterized by lung abnormalities, including the presence of syncytial pneumocytes. Syncytia form when SARS‐CoV‐2 spike protein expressed on the surface of infected cells interacts with the ACE2 receptor on neighboring cells. The syncytia forming potential of spike variant prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajah, Maaran Michael, Hubert, Mathieu, Bishop, Elodie, Saunders, Nell, Robinot, Remy, Grzelak, Ludivine, Planas, Delphine, Dufloo, Jérémy, Gellenoncourt, Stacy, Bongers, Alice, Zivaljic, Marija, Planchais, Cyril, Guivel‐Benhassine, Florence, Porrot, Françoise, Mouquet, Hugo, Chakrabarti, Lisa A, Buchrieser, Julian, Schwartz, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646911/ https://www.ncbi.nlm.nih.gov/pubmed/34601723 http://dx.doi.org/10.15252/embj.2021108944

Ejemplares similares

Syncytia formation by SARS‐CoV‐2‐infected cells
por: Buchrieser, Julian, et al.
Publicado: (2020)

Syncytia formation by SARS‐CoV‐2‐infected cells
por: Buchrieser, Julian, et al.
Publicado: (2021)

The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants
por: Gellenoncourt, Stacy, et al.
Publicado: (2022)

The Mechanism and Consequences of SARS-CoV-2 Spike-Mediated Fusion and Syncytia Formation
por: Rajah, Maaran Michael, et al.
Publicado: (2022)

Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies
por: Planas, Delphine, et al.
Publicado: (2022)

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies
por: Planas, Delphine, et al.
Publicado: (2023)

Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells
por: Dufloo, Jérémy, et al.
Publicado: (2022)

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies
por: Dufloo, Jérémy, et al.
Publicado: (2021)

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2
por: Saunders, Nell, et al.
Publicado: (2022)

A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations
por: Grzelak, Ludivine, et al.
Publicado: (2020)

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies
por: Bruel, Timothée, et al.
Publicado: (2022)

HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer
por: Malbec, Marine, et al.
Publicado: (2013)

Syncytia in Fungi
por: Mela, Alexander P., et al.
Publicado: (2020)

Syncytia Formation in Oncolytic Virotherapy
por: Burton, Chase, et al.
Publicado: (2019)

Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2
por: Planchais, Cyril, et al.
Publicado: (2022)

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells
por: Planchais, Cyril, et al.
Publicado: (2019)

The entanglement between flaviviruses and ER-shaping proteins
por: Rajah, Maaran Michael, et al.
Publicado: (2020)

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study
por: Monel, Blandine, et al.
Publicado: (2021)

Communal living: the role of polyploidy and syncytia in tissue biology
por: Peterson, Nora G., et al.
Publicado: (2021)

Permissiveness and competition within and between Neurospora crassa syncytia
por: Mela, Alexander P, et al.
Publicado: (2023)

Contemporary Zika Virus Isolates Induce More dsRNA and Produce More Negative-Strand Intermediate in Human Astrocytoma Cells
por: Barnard, Trisha R., et al.
Publicado: (2018)

Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry
por: Claireaux, Mathieu, et al.
Publicado: (2022)

ON THE ROLE OF MICROTUBULES IN MOVEMENT AND ALIGNMENT OF NUCLEI IN VIRUS-INDUCED SYNCYTIA
por: Holmes, Kathryn V., et al.
Publicado: (1968)

Diversity and activity of sugar transporters in nematode-induced root syncytia
por: Hofmann, Julia, et al.
Publicado: (2009)

Impact of Induced Syncytia Formation on the Oncolytic Potential of Myxoma Virus
por: Burton, Chase, et al.
Publicado: (2019)

Profiling the Proteome of Cyst Nematode-Induced Syncytia on Tomato Roots
por: Filipecki, Marcin, et al.
Publicado: (2021)

Involvement of microtubules and 10-nm filaments in the movement and positioning of nuclei in syncytia
Publicado: (1979)

The F-actin cytoskeleton in syncytia from non-clonal progenitor cells
por: Płachno, Bartosz Jan, et al.
Publicado: (2010)

The transcriptome of syncytia induced by the cyst nematode Heterodera schachtii in Arabidopsis roots
por: Szakasits, Dagmar, et al.
Publicado: (2009)

Drivers and Distribution of Henipavirus-Induced Syncytia: What Do We Know?
por: Gamble, Amandine, et al.
Publicado: (2021)

Autophagy–mediated plasma membrane removal promotes the formation of epithelial syncytia
por: Kakanj, Parisa, et al.
Publicado: (2022)

Elimination of HIV-1-infected cells by broadly neutralizing antibodies
por: Bruel, Timothée, et al.
Publicado: (2016)

Active Adenoviral Vascular Penetration by Targeted Formation of Heterocellular Endothelial–epithelial Syncytia
por: Chen, Hannah H, et al.
Publicado: (2011)

Cell-to-cell spread of microsporidia causes Caenorhabditis elegans organs to form syncytia
por: Balla, Keir M., et al.
Publicado: (2016)

Acidic pH induces fusion of cells infected with baculovirus to form syncytia
por: Leikina, Evgenia, et al.
Publicado: (1992)

Syncytia Formation Induced by Coronavirus Infection Is Associated with Fragmentation and Rearrangement of the Golgi Apparatus
por: LAVI, EHUD, et al.
Publicado: (1996)

Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia
por: Asarnow, Daniel, et al.
Publicado: (2021)

Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair
por: White, James S., et al.
Publicado: (2023)

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells
por: Casartelli, Nicoletta, et al.
Publicado: (2010)

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
por: Prigent, Julie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l11vq5migsb09fmbo99q9lhgqn