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1,25-Dihydroxyvitamin D(3) attenuates IL-1β secretion by suppressing NLRP1 inflammasome activation by upregulating the NRF2-HO-1 pathway in epidermal keratinocytes

The nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein (NLRP) inflammasome is a key inflammatory signaling pathway activated via a two-step signaling process consisting of priming and activation steps. Several studies have shown that 1,25-dihydroxyvitamin...

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Detalles Bibliográficos
Autores principales: Nakajo, Takahisa, Katayoshi, Takeshi, Kitajima, Natsuko, Tsuji-Naito, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646996/
https://www.ncbi.nlm.nih.gov/pubmed/34872043
http://dx.doi.org/10.1016/j.redox.2021.102203

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