Npas4 regulates medium spiny neuron physiology and gates cocaine‐induced hyperlocomotion

We show here that the transcription factor Npas4 is an important regulator of medium spiny neuron spine density and electrophysiological parameters and that it determines the magnitude of cocaine‐induced hyperlocomotion in mice. Npas4 is induced by synaptic stimuli that cause calcium influx, but not...

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Detalles Bibliográficos
Autores principales: Lissek, Thomas, Andrianarivelo, Andry, Saint‐Jour, Estefani, Allichon, Marie‐Charlotte, Bauersachs, Hanke Gwendolyn, Nassar, Merie, Piette, Charlotte, Pruunsild, Priit, Tan, Yan‐Wei, Forget, Benoit, Heck, Nicolas, Caboche, Jocelyne, Venance, Laurent, Vanhoutte, Peter, Bading, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647009/
https://www.ncbi.nlm.nih.gov/pubmed/34661342
http://dx.doi.org/10.15252/embr.202051882

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