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Diplopia as the First Sign of Gastric Carcinoma

Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carcinoma to an extraocular eye muscle is extremely ra...

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Autores principales: Roohé, Suzanna L., Gan, Ivan M., van der Weerd, Kim, Lopuhaä, Boaz, Verdijk, Robert M., Paridaens, Dion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647119/
https://www.ncbi.nlm.nih.gov/pubmed/34950013
http://dx.doi.org/10.1159/000519953
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author Roohé, Suzanna L.
Gan, Ivan M.
van der Weerd, Kim
Lopuhaä, Boaz
Verdijk, Robert M.
Paridaens, Dion
author_facet Roohé, Suzanna L.
Gan, Ivan M.
van der Weerd, Kim
Lopuhaä, Boaz
Verdijk, Robert M.
Paridaens, Dion
author_sort Roohé, Suzanna L.
collection PubMed
description Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carcinoma to an extraocular eye muscle is extremely rare. A solitary thickening in an extraocular eye muscle with no inflammatory features is suspect for a tumor. Symptoms such as diplopia, proptosis, ptosis, vision loss, or pain may be associated with an orbital malignancy. Our patient, a 67-year-old man known with radically resected prostate cancer, presented with complaints of vertigo with a tendency to fall, headache, and diplopia when looking to the right. As a coincidental finding, swelling of the rectus lateralis muscle of the left eye was observed on imaging. Extensive additional investigations showed that a gastric carcinoma with intraorbital and leptomeningeal metastasis was the cause. In conclusion, a solitary thickened extraocular eye muscle should be recognized in time and examined further.
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spelling pubmed-86471192021-12-22 Diplopia as the First Sign of Gastric Carcinoma Roohé, Suzanna L. Gan, Ivan M. van der Weerd, Kim Lopuhaä, Boaz Verdijk, Robert M. Paridaens, Dion Case Rep Ophthalmol Case Report Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carcinoma to an extraocular eye muscle is extremely rare. A solitary thickening in an extraocular eye muscle with no inflammatory features is suspect for a tumor. Symptoms such as diplopia, proptosis, ptosis, vision loss, or pain may be associated with an orbital malignancy. Our patient, a 67-year-old man known with radically resected prostate cancer, presented with complaints of vertigo with a tendency to fall, headache, and diplopia when looking to the right. As a coincidental finding, swelling of the rectus lateralis muscle of the left eye was observed on imaging. Extensive additional investigations showed that a gastric carcinoma with intraorbital and leptomeningeal metastasis was the cause. In conclusion, a solitary thickened extraocular eye muscle should be recognized in time and examined further. S. Karger AG 2021-10-26 /pmc/articles/PMC8647119/ /pubmed/34950013 http://dx.doi.org/10.1159/000519953 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Roohé, Suzanna L.
Gan, Ivan M.
van der Weerd, Kim
Lopuhaä, Boaz
Verdijk, Robert M.
Paridaens, Dion
Diplopia as the First Sign of Gastric Carcinoma
title Diplopia as the First Sign of Gastric Carcinoma
title_full Diplopia as the First Sign of Gastric Carcinoma
title_fullStr Diplopia as the First Sign of Gastric Carcinoma
title_full_unstemmed Diplopia as the First Sign of Gastric Carcinoma
title_short Diplopia as the First Sign of Gastric Carcinoma
title_sort diplopia as the first sign of gastric carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647119/
https://www.ncbi.nlm.nih.gov/pubmed/34950013
http://dx.doi.org/10.1159/000519953
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