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Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review

Burkitt lymphoma (BL) is a highly aggressive B-cell neoplasm that is well known to be associated with HIV. The presentation usually reflects the underline immunodeficiency state (like opportunistic infections and chronic diarrhea, and enlarged lymph nodes). The most common causes for 3rd cranial ner...

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Autores principales: Abdelmahmuod, Elabbass A., Abdulgayoom, Mohammed, Elhadi, Mohammed, Magboul, Hiba, Sharaf Eldean, Mouhammad Z., Alatasi, Sali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647132/
https://www.ncbi.nlm.nih.gov/pubmed/34949995
http://dx.doi.org/10.1159/000514983
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author Abdelmahmuod, Elabbass A.
Abdulgayoom, Mohammed
Elhadi, Mohammed
Magboul, Hiba
Sharaf Eldean, Mouhammad Z.
Alatasi, Sali
author_facet Abdelmahmuod, Elabbass A.
Abdulgayoom, Mohammed
Elhadi, Mohammed
Magboul, Hiba
Sharaf Eldean, Mouhammad Z.
Alatasi, Sali
author_sort Abdelmahmuod, Elabbass A.
collection PubMed
description Burkitt lymphoma (BL) is a highly aggressive B-cell neoplasm that is well known to be associated with HIV. The presentation usually reflects the underline immunodeficiency state (like opportunistic infections and chronic diarrhea, and enlarged lymph nodes). The most common causes for 3rd cranial nerve palsy are intracranial aneurysm, ischemia, trauma, and migraine. But for our case, it turned out to be associated with underline HIV and BL, which is an unusual cause. Here, we present a 43-year-old gentleman with no past medical history presented to the emergency department with 4 days history of drooping of left eyelid and headache and binocular diplopia with no other neurological features. CT abdomen showed lymph node enlargement. Lymph node biopsy showed the characteristic of Burkitt's cell lymphoma. He was started on chemotherapy, but unfortunately, he died. We're enlightening this case of an isolated oculomotor nerve palsy to diagnose lethal pathology like disseminated BL.
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spelling pubmed-86471322021-12-22 Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review Abdelmahmuod, Elabbass A. Abdulgayoom, Mohammed Elhadi, Mohammed Magboul, Hiba Sharaf Eldean, Mouhammad Z. Alatasi, Sali Case Rep Oncol Case Report Burkitt lymphoma (BL) is a highly aggressive B-cell neoplasm that is well known to be associated with HIV. The presentation usually reflects the underline immunodeficiency state (like opportunistic infections and chronic diarrhea, and enlarged lymph nodes). The most common causes for 3rd cranial nerve palsy are intracranial aneurysm, ischemia, trauma, and migraine. But for our case, it turned out to be associated with underline HIV and BL, which is an unusual cause. Here, we present a 43-year-old gentleman with no past medical history presented to the emergency department with 4 days history of drooping of left eyelid and headache and binocular diplopia with no other neurological features. CT abdomen showed lymph node enlargement. Lymph node biopsy showed the characteristic of Burkitt's cell lymphoma. He was started on chemotherapy, but unfortunately, he died. We're enlightening this case of an isolated oculomotor nerve palsy to diagnose lethal pathology like disseminated BL. S. Karger AG 2021-10-27 /pmc/articles/PMC8647132/ /pubmed/34949995 http://dx.doi.org/10.1159/000514983 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Abdelmahmuod, Elabbass A.
Abdulgayoom, Mohammed
Elhadi, Mohammed
Magboul, Hiba
Sharaf Eldean, Mouhammad Z.
Alatasi, Sali
Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title_full Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title_fullStr Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title_full_unstemmed Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title_short Isolated Oculomotor Cranial Nerve Palsy as Unusual Presentation of Primary High-Grade Burkitt's Cell Lymphoma in HIV Patient: Case Report and Literature Review
title_sort isolated oculomotor cranial nerve palsy as unusual presentation of primary high-grade burkitt's cell lymphoma in hiv patient: case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647132/
https://www.ncbi.nlm.nih.gov/pubmed/34949995
http://dx.doi.org/10.1159/000514983
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