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Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Peripheral Mononuclear Cells in Patients With Ankylosing Spondylitis

OBJECTIVE: Genetic studies on ankylosing spondylitis (AS) have identified more than 100 pathogenic genes. Building a bridge between these genes and biologically targeted therapies is the current research hotspot. METHODS: We integrated single-cell assaying transposase-accessible chromatin sequencing...

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Detalles Bibliográficos
Autores principales:	Xu, Huixuan, Yu, Haiyan, Liu, Lixiong, Wu, Hongwei, Zhang, Cantong, Cai, Wanxia, Hong, Xiaoping, Liu, Dongzhou, Tang, Donge, Dai, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647172/ https://www.ncbi.nlm.nih.gov/pubmed/34880858 http://dx.doi.org/10.3389/fimmu.2021.760381

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