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Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection

AIM: The aim of the current study was to evaluate the prevalence of coronavirus disease (COVID‐19) in methanol‐poisoned patients admitted to two toxicology academic centers during the COVID‐19 outbreak and determine their clinical features and chest/brain computed tomography (CT) findings. METHODS:...

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Autores principales: Zamani, Nasim, Gheshlaghi, Farzad, Haghighi‐Morad, Maryam, Bahrami‐Motlagh, Hooman, Alavi Darazam, Ilad, Hadeiy, Seyed Kaveh, McDonald, Rebecca, Hassanian‐Moghaddam, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647202/
https://www.ncbi.nlm.nih.gov/pubmed/34925862
http://dx.doi.org/10.1002/ams2.715
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author Zamani, Nasim
Gheshlaghi, Farzad
Haghighi‐Morad, Maryam
Bahrami‐Motlagh, Hooman
Alavi Darazam, Ilad
Hadeiy, Seyed Kaveh
McDonald, Rebecca
Hassanian‐Moghaddam, Hossein
author_facet Zamani, Nasim
Gheshlaghi, Farzad
Haghighi‐Morad, Maryam
Bahrami‐Motlagh, Hooman
Alavi Darazam, Ilad
Hadeiy, Seyed Kaveh
McDonald, Rebecca
Hassanian‐Moghaddam, Hossein
author_sort Zamani, Nasim
collection PubMed
description AIM: The aim of the current study was to evaluate the prevalence of coronavirus disease (COVID‐19) in methanol‐poisoned patients admitted to two toxicology academic centers during the COVID‐19 outbreak and determine their clinical features and chest/brain computed tomography (CT) findings. METHODS: Methanol‐poisoned patients who had been referred during the COVID‐19 pandemic were evaluated for signs and symptoms of COVID‐19 by chest CT scans and/or polymerase chain reaction test. RESULTS: A total of 62 patients with confirmed methanol poisoning were enrolled in the study, with a median (interquartile range) age of 35 (28–44) years. Thirty‐nine (62.9%) survived. Nine (14.5%) were diagnosed to have COVID‐19, of whom four survived. There was a significant correlation between COVID‐19 disease and a history of alcohol consumption (p = 0.036; odds ratio 1.7; 95% confidence interval, 1.3–2.2). Univariate analysis showed significant differences between infected and noninfected patients regarding their urea and time for first and second hemodialysis sessions, as well as the duration of ethanol administration. CONCLUSIONS: In conclusion, during the pandemic, specific attention should be paid to patients with a history of alcohol ingestion and elevated creatinine, loss of consciousness, and severe acidosis as these signs/symptoms could be present in both COVID‐19 and methanol poisoning, making differentiation between the two challenging.
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spelling pubmed-86472022021-12-17 Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection Zamani, Nasim Gheshlaghi, Farzad Haghighi‐Morad, Maryam Bahrami‐Motlagh, Hooman Alavi Darazam, Ilad Hadeiy, Seyed Kaveh McDonald, Rebecca Hassanian‐Moghaddam, Hossein Acute Med Surg Original Articles AIM: The aim of the current study was to evaluate the prevalence of coronavirus disease (COVID‐19) in methanol‐poisoned patients admitted to two toxicology academic centers during the COVID‐19 outbreak and determine their clinical features and chest/brain computed tomography (CT) findings. METHODS: Methanol‐poisoned patients who had been referred during the COVID‐19 pandemic were evaluated for signs and symptoms of COVID‐19 by chest CT scans and/or polymerase chain reaction test. RESULTS: A total of 62 patients with confirmed methanol poisoning were enrolled in the study, with a median (interquartile range) age of 35 (28–44) years. Thirty‐nine (62.9%) survived. Nine (14.5%) were diagnosed to have COVID‐19, of whom four survived. There was a significant correlation between COVID‐19 disease and a history of alcohol consumption (p = 0.036; odds ratio 1.7; 95% confidence interval, 1.3–2.2). Univariate analysis showed significant differences between infected and noninfected patients regarding their urea and time for first and second hemodialysis sessions, as well as the duration of ethanol administration. CONCLUSIONS: In conclusion, during the pandemic, specific attention should be paid to patients with a history of alcohol ingestion and elevated creatinine, loss of consciousness, and severe acidosis as these signs/symptoms could be present in both COVID‐19 and methanol poisoning, making differentiation between the two challenging. John Wiley and Sons Inc. 2021-12-06 /pmc/articles/PMC8647202/ /pubmed/34925862 http://dx.doi.org/10.1002/ams2.715 Text en © 2021 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Zamani, Nasim
Gheshlaghi, Farzad
Haghighi‐Morad, Maryam
Bahrami‐Motlagh, Hooman
Alavi Darazam, Ilad
Hadeiy, Seyed Kaveh
McDonald, Rebecca
Hassanian‐Moghaddam, Hossein
Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title_full Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title_fullStr Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title_full_unstemmed Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title_short Prevalence of clinical and radiologic features in methanol‐poisoned patients with and without COVID‐19 infection
title_sort prevalence of clinical and radiologic features in methanol‐poisoned patients with and without covid‐19 infection
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647202/
https://www.ncbi.nlm.nih.gov/pubmed/34925862
http://dx.doi.org/10.1002/ams2.715
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