Leflunomide Inhibits rat-to-Mouse Cardiac Xenograft Rejection by Suppressing Adaptive Immune Cell Response and NF-κB Signaling Activation

Xenotransplantation is a potential solution for the severe shortage of human donor organs and tissues. The generation of humanized animal models attenuates strong innate immune responses, such as complement-mediated hyperacute rejection. However, acute vascular rejection and cell mediated rejection...

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Detalles Bibliográficos
Autores principales: Ma, Yunhan, Xie, Baiyi, Guo, Junjun, Chen, Yingyu, Zhong, Mengya, Lin, Qingru, Hua, Jianyu, Zhong, Jiaying, Luo, Xuewei, Yan, Guoliang, Dai, Helong, Qi, Zhongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647224/
https://www.ncbi.nlm.nih.gov/pubmed/34814739
http://dx.doi.org/10.1177/09636897211054503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647224/
https://www.ncbi.nlm.nih.gov/pubmed/34814739
http://dx.doi.org/10.1177/09636897211054503

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