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A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases

OBJECTIVE: Spondylodiscitis is an important clinical a problem requiring serious approaches. In this study, we sought to raise awareness by examining the epidemiology and laboratory, clinical, and radiological findings of spondylodiscitis, which sometimes has a delayed diagnosis and which can be dif...

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Autores principales: Kaya, Safak, Kaya, Sehmuz, Kavak, Seyhmus, Comoglu, Senol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647245/
https://www.ncbi.nlm.nih.gov/pubmed/34851766
http://dx.doi.org/10.1177/03000605211060197
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author Kaya, Safak
Kaya, Sehmuz
Kavak, Seyhmus
Comoglu, Senol
author_facet Kaya, Safak
Kaya, Sehmuz
Kavak, Seyhmus
Comoglu, Senol
author_sort Kaya, Safak
collection PubMed
description OBJECTIVE: Spondylodiscitis is an important clinical a problem requiring serious approaches. In this study, we sought to raise awareness by examining the epidemiology and laboratory, clinical, and radiological findings of spondylodiscitis, which sometimes has a delayed diagnosis and which can be difficult to treat. METHODS: In total, 343 patients with spondylodiscitis were included in the study. RESULTS: The patients were classified as having as pyogenic (n = 153, 44.6%), brucellar (n = 138, 40.2%), or tuberculous (n = 52, 15.2%) spondylodiscitis. Meanwhile, 281 patients underwent magnetic resonance imaging, 71 underwent computed tomography, and 17 underwent scintigraphy for diagnosis. The rates of involvement at more than two segments and paraspinal abscess were significantly higher in tuberculous spondylodiscitis. However, disc involvement was significantly more common in brucellar and pyogenic spondylodiscitis. CONCLUSION: The incidence of spondylodiscitis has increased substantially, especially in the young population. The invasive procedures and high rate of culture negativity make the diagnosis difficult. Therefore, clinical and radiological findings are useful in the diagnosis of spondylodiscitis. Despite the high rate of culture negativity, every effort should be made to identify the causative organism using invasive methods.
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spelling pubmed-86472452021-12-07 A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases Kaya, Safak Kaya, Sehmuz Kavak, Seyhmus Comoglu, Senol J Int Med Res Retrospective Clinical Research Report OBJECTIVE: Spondylodiscitis is an important clinical a problem requiring serious approaches. In this study, we sought to raise awareness by examining the epidemiology and laboratory, clinical, and radiological findings of spondylodiscitis, which sometimes has a delayed diagnosis and which can be difficult to treat. METHODS: In total, 343 patients with spondylodiscitis were included in the study. RESULTS: The patients were classified as having as pyogenic (n = 153, 44.6%), brucellar (n = 138, 40.2%), or tuberculous (n = 52, 15.2%) spondylodiscitis. Meanwhile, 281 patients underwent magnetic resonance imaging, 71 underwent computed tomography, and 17 underwent scintigraphy for diagnosis. The rates of involvement at more than two segments and paraspinal abscess were significantly higher in tuberculous spondylodiscitis. However, disc involvement was significantly more common in brucellar and pyogenic spondylodiscitis. CONCLUSION: The incidence of spondylodiscitis has increased substantially, especially in the young population. The invasive procedures and high rate of culture negativity make the diagnosis difficult. Therefore, clinical and radiological findings are useful in the diagnosis of spondylodiscitis. Despite the high rate of culture negativity, every effort should be made to identify the causative organism using invasive methods. SAGE Publications 2021-12-01 /pmc/articles/PMC8647245/ /pubmed/34851766 http://dx.doi.org/10.1177/03000605211060197 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Kaya, Safak
Kaya, Sehmuz
Kavak, Seyhmus
Comoglu, Senol
A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title_full A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title_fullStr A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title_full_unstemmed A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title_short A disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
title_sort disease that is difficult to diagnose and treat: evaluation of 343 spondylodiscitis cases
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647245/
https://www.ncbi.nlm.nih.gov/pubmed/34851766
http://dx.doi.org/10.1177/03000605211060197
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