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Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai

OBJECTIVE: Caries risk assessment tools are essential for identifying and providing treatment for individuals at high risk of developing caries. We aimed to develop a nomogram for the assessment and evaluation of caries risk among Chinese children. METHODS: We enrolled schoolchildren age 7 years fro...

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Autores principales: Luo, Yuan, Zhang, Hao, Zeng, Xiaoli, Xu, Wei, Wang, Xun, Zhang, Ying, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647255/
https://www.ncbi.nlm.nih.gov/pubmed/34851774
http://dx.doi.org/10.1177/03000605211060175
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author Luo, Yuan
Zhang, Hao
Zeng, Xiaoli
Xu, Wei
Wang, Xun
Zhang, Ying
Wang, Yan
author_facet Luo, Yuan
Zhang, Hao
Zeng, Xiaoli
Xu, Wei
Wang, Xun
Zhang, Ying
Wang, Yan
author_sort Luo, Yuan
collection PubMed
description OBJECTIVE: Caries risk assessment tools are essential for identifying and providing treatment for individuals at high risk of developing caries. We aimed to develop a nomogram for the assessment and evaluation of caries risk among Chinese children. METHODS: We enrolled schoolchildren age 7 years from a primary school in Shanghai. Baseline information of participants was collected using a questionnaire completed by children’s caregivers. A nomogram of a novel prediction scoring model was established based on predictors detected in univariate and multivariate analyses. Predictive accuracy and discriminative ability of the nomogram were calculated using the concordance index (C index). The bootstrap method (1000 samples) was used to decrease overfitting. The net benefit of the model was validated using decision curve analysis. RESULTS: Overall, 406 children with complete information and two completed dental examinations were included in the final analysis. The nomogram based on logistic regression model coefficients demonstrated a C index of 0.766 (95% confidence interval: 0.761–0.771) for caries risk. The net benefit of the decision curve analysis was 38.6% at 55% threshold probability. CONCLUSION: This nomogram model, derived using dietary habits, oral hygiene status, and caries experience, showed promising predictive ability to assess the caries risk among Chinese children.
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spelling pubmed-86472552021-12-07 Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai Luo, Yuan Zhang, Hao Zeng, Xiaoli Xu, Wei Wang, Xun Zhang, Ying Wang, Yan J Int Med Res Retrospective Clinical Research Report OBJECTIVE: Caries risk assessment tools are essential for identifying and providing treatment for individuals at high risk of developing caries. We aimed to develop a nomogram for the assessment and evaluation of caries risk among Chinese children. METHODS: We enrolled schoolchildren age 7 years from a primary school in Shanghai. Baseline information of participants was collected using a questionnaire completed by children’s caregivers. A nomogram of a novel prediction scoring model was established based on predictors detected in univariate and multivariate analyses. Predictive accuracy and discriminative ability of the nomogram were calculated using the concordance index (C index). The bootstrap method (1000 samples) was used to decrease overfitting. The net benefit of the model was validated using decision curve analysis. RESULTS: Overall, 406 children with complete information and two completed dental examinations were included in the final analysis. The nomogram based on logistic regression model coefficients demonstrated a C index of 0.766 (95% confidence interval: 0.761–0.771) for caries risk. The net benefit of the decision curve analysis was 38.6% at 55% threshold probability. CONCLUSION: This nomogram model, derived using dietary habits, oral hygiene status, and caries experience, showed promising predictive ability to assess the caries risk among Chinese children. SAGE Publications 2021-12-01 /pmc/articles/PMC8647255/ /pubmed/34851774 http://dx.doi.org/10.1177/03000605211060175 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Luo, Yuan
Zhang, Hao
Zeng, Xiaoli
Xu, Wei
Wang, Xun
Zhang, Ying
Wang, Yan
Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title_full Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title_fullStr Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title_full_unstemmed Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title_short Nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in Shanghai
title_sort nomogram prediction of caries risk among schoolchildren age 7 years based on a cohort study in shanghai
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647255/
https://www.ncbi.nlm.nih.gov/pubmed/34851774
http://dx.doi.org/10.1177/03000605211060175
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