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Live imaging of transcription sites using an elongating RNA polymerase II–specific probe

In eukaryotic nuclei, most genes are transcribed by RNA polymerase II (RNAP2), whose regulation is a key to understanding the genome and cell function. RNAP2 has a long heptapeptide repeat (Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7), and Ser2 is phosphorylated on an elongation form. To detect RNAP2 Ser2 ph...

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Detalles Bibliográficos
Autores principales:	Uchino, Satoshi, Ito, Yuma, Sato, Yuko, Handa, Tetsuya, Ohkawa, Yasuyuki, Tokunaga, Makio, Kimura, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Tools
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647360/ https://www.ncbi.nlm.nih.gov/pubmed/34854870 http://dx.doi.org/10.1083/jcb.202104134

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