Exploration of Dark Chemical Genomics Space via Portal Learning: Applied to Targeting the Undruggable Genome and COVID-19 Anti-Infective Polypharmacology

Advances in biomedicine are largely fueled by exploring uncharted territories of human biology. Machine learning can both enable and accelerate discovery, but faces a fundamental hurdle when applied to unseen data with distributions that differ from previously observed ones—a common dilemma in scien...

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Detalles Bibliográficos
Autores principales: Cai, Tian, Xie, Li, Chen, Muge, Liu, Yang, He, Di, Zhang, Shuo, Mura, Cameron, Bourne, Philip E., Xie, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647653/
https://www.ncbi.nlm.nih.gov/pubmed/34873596
http://dx.doi.org/10.21203/rs.3.rs-1109318/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647653/
https://www.ncbi.nlm.nih.gov/pubmed/34873596
http://dx.doi.org/10.21203/rs.3.rs-1109318/v1

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