Natural SINEUP RNAs in Autism Spectrum Disorders: RAB11B-AS1 Dysregulation in a Neuronal CHD8 Suppression Model Leads to RAB11B Protein Increase

CHD8 represents one of the highest confidence genetic risk factors implied in Autism Spectrum Disorders, with most mutations leading to CHD8 haploinsufficiency and the insurgence of specific phenotypes, such as macrocephaly, facial dysmorphisms, intellectual disability, and gastrointestinal complain...

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Detalles Bibliográficos
Autores principales: Zarantonello, Giulia, Arnoldi, Michele, Filosi, Michele, Tebaldi, Toma, Spirito, Giovanni, Barbieri, Anna, Gustincich, Stefano, Sanges, Remo, Domenici, Enrico, Di Leva, Francesca, Biagioli, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647803/
https://www.ncbi.nlm.nih.gov/pubmed/34880900
http://dx.doi.org/10.3389/fgene.2021.745229

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