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Oral Beta-blocker in Problematic Infantile Hemangioma

One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. T...

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Autores principales: AlHasan, Rashed N., Arabiyat, Lamees, Ammar, Hamad M., Louri, Nayef A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647869/
https://www.ncbi.nlm.nih.gov/pubmed/34881149
http://dx.doi.org/10.1097/GOX.0000000000003581
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author AlHasan, Rashed N.
Arabiyat, Lamees
Ammar, Hamad M.
Louri, Nayef A.
author_facet AlHasan, Rashed N.
Arabiyat, Lamees
Ammar, Hamad M.
Louri, Nayef A.
author_sort AlHasan, Rashed N.
collection PubMed
description One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. This study reports a case of girl aged 3 years, 7 months, diagnosed with periorbital infantile hemangioma that was successfully treated with oral propranolol in specific doses and gradual tapering off dose. The patient had marked involution of the lesion with no significant side effects after starting her treatment at the age of 4 months, for a total of 13 months with no reported rebound growth after almost 2 years since the termination of treatment. Oral beta-blockers can be used safely in treatment of problematic infantile hemangioma as a single modality, without any surgical intervention.
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spelling pubmed-86478692021-12-07 Oral Beta-blocker in Problematic Infantile Hemangioma AlHasan, Rashed N. Arabiyat, Lamees Ammar, Hamad M. Louri, Nayef A. Plast Reconstr Surg Glob Open Craniofacial/Pediatric One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. This study reports a case of girl aged 3 years, 7 months, diagnosed with periorbital infantile hemangioma that was successfully treated with oral propranolol in specific doses and gradual tapering off dose. The patient had marked involution of the lesion with no significant side effects after starting her treatment at the age of 4 months, for a total of 13 months with no reported rebound growth after almost 2 years since the termination of treatment. Oral beta-blockers can be used safely in treatment of problematic infantile hemangioma as a single modality, without any surgical intervention. Lippincott Williams & Wilkins 2021-05-18 /pmc/articles/PMC8647869/ /pubmed/34881149 http://dx.doi.org/10.1097/GOX.0000000000003581 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Craniofacial/Pediatric
AlHasan, Rashed N.
Arabiyat, Lamees
Ammar, Hamad M.
Louri, Nayef A.
Oral Beta-blocker in Problematic Infantile Hemangioma
title Oral Beta-blocker in Problematic Infantile Hemangioma
title_full Oral Beta-blocker in Problematic Infantile Hemangioma
title_fullStr Oral Beta-blocker in Problematic Infantile Hemangioma
title_full_unstemmed Oral Beta-blocker in Problematic Infantile Hemangioma
title_short Oral Beta-blocker in Problematic Infantile Hemangioma
title_sort oral beta-blocker in problematic infantile hemangioma
topic Craniofacial/Pediatric
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647869/
https://www.ncbi.nlm.nih.gov/pubmed/34881149
http://dx.doi.org/10.1097/GOX.0000000000003581
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