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Oral Beta-blocker in Problematic Infantile Hemangioma
One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. T...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647869/ https://www.ncbi.nlm.nih.gov/pubmed/34881149 http://dx.doi.org/10.1097/GOX.0000000000003581 |
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author | AlHasan, Rashed N. Arabiyat, Lamees Ammar, Hamad M. Louri, Nayef A. |
author_facet | AlHasan, Rashed N. Arabiyat, Lamees Ammar, Hamad M. Louri, Nayef A. |
author_sort | AlHasan, Rashed N. |
collection | PubMed |
description | One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. This study reports a case of girl aged 3 years, 7 months, diagnosed with periorbital infantile hemangioma that was successfully treated with oral propranolol in specific doses and gradual tapering off dose. The patient had marked involution of the lesion with no significant side effects after starting her treatment at the age of 4 months, for a total of 13 months with no reported rebound growth after almost 2 years since the termination of treatment. Oral beta-blockers can be used safely in treatment of problematic infantile hemangioma as a single modality, without any surgical intervention. |
format | Online Article Text |
id | pubmed-8647869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-86478692021-12-07 Oral Beta-blocker in Problematic Infantile Hemangioma AlHasan, Rashed N. Arabiyat, Lamees Ammar, Hamad M. Louri, Nayef A. Plast Reconstr Surg Glob Open Craniofacial/Pediatric One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic hemangiomas, interfering with function or aesthetic appearance. This study reports a case of girl aged 3 years, 7 months, diagnosed with periorbital infantile hemangioma that was successfully treated with oral propranolol in specific doses and gradual tapering off dose. The patient had marked involution of the lesion with no significant side effects after starting her treatment at the age of 4 months, for a total of 13 months with no reported rebound growth after almost 2 years since the termination of treatment. Oral beta-blockers can be used safely in treatment of problematic infantile hemangioma as a single modality, without any surgical intervention. Lippincott Williams & Wilkins 2021-05-18 /pmc/articles/PMC8647869/ /pubmed/34881149 http://dx.doi.org/10.1097/GOX.0000000000003581 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Craniofacial/Pediatric AlHasan, Rashed N. Arabiyat, Lamees Ammar, Hamad M. Louri, Nayef A. Oral Beta-blocker in Problematic Infantile Hemangioma |
title | Oral Beta-blocker in Problematic Infantile Hemangioma |
title_full | Oral Beta-blocker in Problematic Infantile Hemangioma |
title_fullStr | Oral Beta-blocker in Problematic Infantile Hemangioma |
title_full_unstemmed | Oral Beta-blocker in Problematic Infantile Hemangioma |
title_short | Oral Beta-blocker in Problematic Infantile Hemangioma |
title_sort | oral beta-blocker in problematic infantile hemangioma |
topic | Craniofacial/Pediatric |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647869/ https://www.ncbi.nlm.nih.gov/pubmed/34881149 http://dx.doi.org/10.1097/GOX.0000000000003581 |
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