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Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best...

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Autores principales: Rosińska-Więckowicz, Anna, Jałowska, Magdalena, Bowszyc-Dmochowska, Monika, Dmochowski, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647993/
https://www.ncbi.nlm.nih.gov/pubmed/34881262
http://dx.doi.org/10.3389/fmed.2021.760823
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author Rosińska-Więckowicz, Anna
Jałowska, Magdalena
Bowszyc-Dmochowska, Monika
Dmochowski, Marian
author_facet Rosińska-Więckowicz, Anna
Jałowska, Magdalena
Bowszyc-Dmochowska, Monika
Dmochowski, Marian
author_sort Rosińska-Więckowicz, Anna
collection PubMed
description Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.
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spelling pubmed-86479932021-12-07 Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative Rosińska-Więckowicz, Anna Jałowska, Magdalena Bowszyc-Dmochowska, Monika Dmochowski, Marian Front Med (Lausanne) Medicine Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with. Frontiers Media S.A. 2021-11-22 /pmc/articles/PMC8647993/ /pubmed/34881262 http://dx.doi.org/10.3389/fmed.2021.760823 Text en Copyright © 2021 Rosińska-Więckowicz, Jałowska, Bowszyc-Dmochowska and Dmochowski. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Rosińska-Więckowicz, Anna
Jałowska, Magdalena
Bowszyc-Dmochowska, Monika
Dmochowski, Marian
Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_full Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_fullStr Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_full_unstemmed Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_short Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
title_sort case report: infantile bullous pemphigoid: triggering by covid-19 is speculative
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647993/
https://www.ncbi.nlm.nih.gov/pubmed/34881262
http://dx.doi.org/10.3389/fmed.2021.760823
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