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Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative
Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647993/ https://www.ncbi.nlm.nih.gov/pubmed/34881262 http://dx.doi.org/10.3389/fmed.2021.760823 |
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author | Rosińska-Więckowicz, Anna Jałowska, Magdalena Bowszyc-Dmochowska, Monika Dmochowski, Marian |
author_facet | Rosińska-Więckowicz, Anna Jałowska, Magdalena Bowszyc-Dmochowska, Monika Dmochowski, Marian |
author_sort | Rosińska-Więckowicz, Anna |
collection | PubMed |
description | Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with. |
format | Online Article Text |
id | pubmed-8647993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86479932021-12-07 Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative Rosińska-Więckowicz, Anna Jałowska, Magdalena Bowszyc-Dmochowska, Monika Dmochowski, Marian Front Med (Lausanne) Medicine Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with. Frontiers Media S.A. 2021-11-22 /pmc/articles/PMC8647993/ /pubmed/34881262 http://dx.doi.org/10.3389/fmed.2021.760823 Text en Copyright © 2021 Rosińska-Więckowicz, Jałowska, Bowszyc-Dmochowska and Dmochowski. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Rosińska-Więckowicz, Anna Jałowska, Magdalena Bowszyc-Dmochowska, Monika Dmochowski, Marian Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title | Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title_full | Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title_fullStr | Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title_full_unstemmed | Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title_short | Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative |
title_sort | case report: infantile bullous pemphigoid: triggering by covid-19 is speculative |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647993/ https://www.ncbi.nlm.nih.gov/pubmed/34881262 http://dx.doi.org/10.3389/fmed.2021.760823 |
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