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Mucinous Adenocarcinoma of the Appendix: The Challenges of Managing a Complex Surgical Case

Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy....

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Detalles Bibliográficos
Autores principales: Vyas, Nirav, Dornseifer, Mamun, Nair, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648134/
https://www.ncbi.nlm.nih.gov/pubmed/34900502
http://dx.doi.org/10.7759/cureus.20157
Descripción
Sumario:Mucinous adenocarcinomas of the appendix are rare and often present as a suspected appendicitis. Diagnostic work-up encompasses colonoscopy, tissue biopsy, CT scan, and a multidisciplinary team input. Management involves surgery, hyperthermic intraperitoneal chemotherapy, and adjuvant chemotherapy. Our patient was known to be human immunodeficiency virus (HIV) positive; therefore, careful consideration had to be taken in starting adjuvant chemotherapy as there were concerns of drug interactions and further immunosuppression. Despite all these challenges the patient has had an excellent outcome with no evidence of recurrence or distant disease.