Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms

Biologics have the potential to induce an immune response when used therapeutically. A number of in vitro assays are currently used preclinically to predict the risk of immunogenicity, but the validation of these preclinical tools suffers from the relatively small number of accessible immunogenic mo...

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Detalles Bibliográficos
Autores principales: Walsh, Robin E., Lannan, Megan, Wen, Yi, Wang, Xiaoli, Moreland, Christopher A., Willency, Jill, Knierman, Michael D., Spindler, Laura, Liu, Ling, Zeng, Wei, Rocha, Guilherme V., Obungu, Victor, Lu, Jirong, Kaliyaperumal, Arunan, Ferrante, Andrea, Siegel, Robert, Malherbe, Laurent P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648324/
https://www.ncbi.nlm.nih.gov/pubmed/32370596
http://dx.doi.org/10.1080/19420862.2020.1764829

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