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A positive feedback regulatory loop involving the lncRNA PVT1 and HIF-1α in pancreatic cancer

Extreme hypoxia is among the most prominent pathogenic features of pancreatic cancer (PC). Both the long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) and hypoxic inducible factor-1α (HIF-1α) are highly expressed in PC patients and play a crucial role in disease progression. Re...

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Detalles Bibliográficos
Autores principales:	Zhu, Yiping, Wu, Fang, Gui, Weiwei, Zhang, Nan, Matro, Erik, Zhu, Linghua, Eserberg, Daniel Turunen, Lin, Xihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648389/ https://www.ncbi.nlm.nih.gov/pubmed/34245303 http://dx.doi.org/10.1093/jmcb/mjab042

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