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An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria

Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the...

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Autores principales: Zaino, Jaafer, Bakri, Abdullah, Al Sayed Ahmad, Amani, Hadba, Ghadeer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648403/
https://www.ncbi.nlm.nih.gov/pubmed/34881206
http://dx.doi.org/10.1055/s-0041-1734387
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author Zaino, Jaafer
Bakri, Abdullah
Al Sayed Ahmad, Amani
Hadba, Ghadeer
author_facet Zaino, Jaafer
Bakri, Abdullah
Al Sayed Ahmad, Amani
Hadba, Ghadeer
author_sort Zaino, Jaafer
collection PubMed
description Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome.
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spelling pubmed-86484032021-12-07 An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria Zaino, Jaafer Bakri, Abdullah Al Sayed Ahmad, Amani Hadba, Ghadeer Avicenna J Med Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome. Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-09-16 /pmc/articles/PMC8648403/ /pubmed/34881206 http://dx.doi.org/10.1055/s-0041-1734387 Text en Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Zaino, Jaafer
Bakri, Abdullah
Al Sayed Ahmad, Amani
Hadba, Ghadeer
An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title_full An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title_fullStr An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title_full_unstemmed An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title_short An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
title_sort arab adolescent with multisystem inflammatory syndrome associated with covid-19: a report from syria
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648403/
https://www.ncbi.nlm.nih.gov/pubmed/34881206
http://dx.doi.org/10.1055/s-0041-1734387
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