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An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria
Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648403/ https://www.ncbi.nlm.nih.gov/pubmed/34881206 http://dx.doi.org/10.1055/s-0041-1734387 |
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author | Zaino, Jaafer Bakri, Abdullah Al Sayed Ahmad, Amani Hadba, Ghadeer |
author_facet | Zaino, Jaafer Bakri, Abdullah Al Sayed Ahmad, Amani Hadba, Ghadeer |
author_sort | Zaino, Jaafer |
collection | PubMed |
description | Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome. |
format | Online Article Text |
id | pubmed-8648403 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86484032021-12-07 An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria Zaino, Jaafer Bakri, Abdullah Al Sayed Ahmad, Amani Hadba, Ghadeer Avicenna J Med Multisystem inflammatory syndrome in children (MIS-C) is a rare and critical condition that affects children following exposure to severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, leading to multiorgan dysfunction and shock. MIS-C has been reported from different parts of the world but rarely from Arab countries. In this report, we describe a 15-year-old Arab boy who was admitted to the ICU during the surge of Coronavirus transmission in Syria with a clinical picture consistent with MIS-C, including high-grade fever, gastrointestinal symptoms, rash, multiorgan dysfunction, and shock. Laboratory profile showed significant elevation of inflammatory markers, negative SARS-CoV-2 RT-PCR testing but positive serologic testing for SARS-CoV-2. The patient received intravenous immunoglobulins (IVIG) and glucocorticoids with remarkable cardiac improvement and significant alleviation in inflammatory markers. To our knowledge, this is the first reported case of MIS-C from Syria, which adds to the epidemiological data about this new syndrome. Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-09-16 /pmc/articles/PMC8648403/ /pubmed/34881206 http://dx.doi.org/10.1055/s-0041-1734387 Text en Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Zaino, Jaafer Bakri, Abdullah Al Sayed Ahmad, Amani Hadba, Ghadeer An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title | An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title_full | An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title_fullStr | An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title_full_unstemmed | An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title_short | An Arab Adolescent with Multisystem Inflammatory Syndrome Associated with COVID-19: A Report from Syria |
title_sort | arab adolescent with multisystem inflammatory syndrome associated with covid-19: a report from syria |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648403/ https://www.ncbi.nlm.nih.gov/pubmed/34881206 http://dx.doi.org/10.1055/s-0041-1734387 |
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