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An interaction Neyman–Scott point process model for coronavirus disease-19

With rapid transmission, the coronavirus disease 2019 (COVID-19) has led to over three million deaths worldwide, posing significant societal challenges. Understanding the spatial patterns of patient visits and detecting local cluster centers are crucial to controlling disease outbreaks. We analyze C...

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Detalles Bibliográficos
Autores principales: Park, Jaewoo, Chang, Won, Choi, Boseung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648587/
https://www.ncbi.nlm.nih.gov/pubmed/34900559
http://dx.doi.org/10.1016/j.spasta.2021.100561
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author Park, Jaewoo
Chang, Won
Choi, Boseung
author_facet Park, Jaewoo
Chang, Won
Choi, Boseung
author_sort Park, Jaewoo
collection PubMed
description With rapid transmission, the coronavirus disease 2019 (COVID-19) has led to over three million deaths worldwide, posing significant societal challenges. Understanding the spatial patterns of patient visits and detecting local cluster centers are crucial to controlling disease outbreaks. We analyze COVID-19 contact tracing data collected from Seoul, which provide a unique opportunity to understand the mechanism of patient visit occurrence. Analyzing contact tracing data is challenging because patient visits show strong clustering patterns, while cluster centers may have complex interaction behavior. Cluster centers attract each other at mid-range distances because other cluster centers are likely to appear in nearby regions. At the same time, they repel each other at too small distances to avoid merging. To account for such behaviors, we develop a novel interaction Neyman–Scott process that regards the observed patient visit events as offsprings generated from a parent cluster center. Inference for such models is challenging since the likelihood involves intractable normalizing functions. To address this issue, we embed an auxiliary variable algorithm into our Markov chain Monte Carlo. We fit our model to several simulated and real data examples under different outbreak scenarios and show that our method can describe the spatial patterns of patient visits well. We also provide useful visualizations that can inform public health interventions for infectious diseases, such as social distancing.
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spelling pubmed-86485872021-12-07 An interaction Neyman–Scott point process model for coronavirus disease-19 Park, Jaewoo Chang, Won Choi, Boseung Spat Stat Article With rapid transmission, the coronavirus disease 2019 (COVID-19) has led to over three million deaths worldwide, posing significant societal challenges. Understanding the spatial patterns of patient visits and detecting local cluster centers are crucial to controlling disease outbreaks. We analyze COVID-19 contact tracing data collected from Seoul, which provide a unique opportunity to understand the mechanism of patient visit occurrence. Analyzing contact tracing data is challenging because patient visits show strong clustering patterns, while cluster centers may have complex interaction behavior. Cluster centers attract each other at mid-range distances because other cluster centers are likely to appear in nearby regions. At the same time, they repel each other at too small distances to avoid merging. To account for such behaviors, we develop a novel interaction Neyman–Scott process that regards the observed patient visit events as offsprings generated from a parent cluster center. Inference for such models is challenging since the likelihood involves intractable normalizing functions. To address this issue, we embed an auxiliary variable algorithm into our Markov chain Monte Carlo. We fit our model to several simulated and real data examples under different outbreak scenarios and show that our method can describe the spatial patterns of patient visits well. We also provide useful visualizations that can inform public health interventions for infectious diseases, such as social distancing. Elsevier B.V. 2022-03 2021-12-07 /pmc/articles/PMC8648587/ /pubmed/34900559 http://dx.doi.org/10.1016/j.spasta.2021.100561 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Park, Jaewoo
Chang, Won
Choi, Boseung
An interaction Neyman–Scott point process model for coronavirus disease-19
title An interaction Neyman–Scott point process model for coronavirus disease-19
title_full An interaction Neyman–Scott point process model for coronavirus disease-19
title_fullStr An interaction Neyman–Scott point process model for coronavirus disease-19
title_full_unstemmed An interaction Neyman–Scott point process model for coronavirus disease-19
title_short An interaction Neyman–Scott point process model for coronavirus disease-19
title_sort interaction neyman–scott point process model for coronavirus disease-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648587/
https://www.ncbi.nlm.nih.gov/pubmed/34900559
http://dx.doi.org/10.1016/j.spasta.2021.100561
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