Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome

Identifying the effects of genetic variation on the epigenome in disease-relevant cell types can help advance our understanding of the first molecular contributions of genetic susceptibility to disease onset. Here, we establish a genome-wide map of DNA methylation quantitative trait loci in CD4(+) T...

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Detalles Bibliográficos
Autores principales: Roostaei, Tina, Klein, Hans-Ulrich, Ma, Yiyi, Felsky, Daniel, Kivisäkk, Pia, Connor, Sarah M., Kroshilina, Alexandra, Yung, Christina, Kaskow, Belinda J., Shao, Xiaorong, Rhead, Brooke, Ordovás, José M., Absher, Devin M., Arnett, Donna K., Liu, Jia, Patsopoulos, Nikolaos, Barcellos, Lisa F., Weiner, Howard L., De Jager, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648735/
https://www.ncbi.nlm.nih.gov/pubmed/34873174
http://dx.doi.org/10.1038/s41467-021-27427-w

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