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The effect of paclitaxel on apoptosis, autophagy and mitotic catastrophe in AGS cells

Paclitaxel is an anti-microtubule agent that has been shown to induce cell death in gastric cancer. However, the detailed mechanism of action is unclear. In this study, we reveal that the paclitaxel-induced cell death mechanism involves mitotic catastrophe, autophagy and apoptosis in AGS cells. Pacl...

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Detalles Bibliográficos
Autores principales: Khing, Tin Myo, Choi, Won Seok, Kim, Dong Min, Po, Wah Wah, Thein, Wynn, Shin, Chang Yell, Sohn, Uy Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648765/
https://www.ncbi.nlm.nih.gov/pubmed/34873207
http://dx.doi.org/10.1038/s41598-021-02503-9