Molecular drivers of tumor progression in microsatellite stable APC mutation-negative colorectal cancers

The tumor suppressor gene adenomatous polyposis coli (APC) is the initiating mutation in approximately 80% of all colorectal cancers (CRC), underscoring the importance of aberrant regulation of intracellular WNT signaling in CRC development. Recent studies have found that early-onset CRC exhibits an...

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Detalles Bibliográficos
Autores principales: Grant, Adam, Xicola, Rosa M., Nguyen, Vivian, Lim, James, Thorne, Curtis, Salhia, Bodour, Llor, Xavier, Ellis, Nathan, Padi, Megha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648784/
https://www.ncbi.nlm.nih.gov/pubmed/34873211
http://dx.doi.org/10.1038/s41598-021-02806-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648784/
https://www.ncbi.nlm.nih.gov/pubmed/34873211
http://dx.doi.org/10.1038/s41598-021-02806-x

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