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Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience.
In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multivariable cox-proportional hazard model was used to estimate th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648798/ https://www.ncbi.nlm.nih.gov/pubmed/34926144 http://dx.doi.org/10.1016/j.lrr.2021.100284 |
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author | Devi, Kanta Shaikh, Muhammad Usman Ali, Natasha Bahadur Adil, Salman Naseem Khan, Maria Soomar, Salman Muhammad |
author_facet | Devi, Kanta Shaikh, Muhammad Usman Ali, Natasha Bahadur Adil, Salman Naseem Khan, Maria Soomar, Salman Muhammad |
author_sort | Devi, Kanta |
collection | PubMed |
description | In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multivariable cox-proportional hazard model was used to estimate the hazard ratios in patients receiving these treatment regimens considering p-value ≤0.05 significant. The survival rate among double/triple expressor lymphoma patients received R-DA-EPOCH was 82.8%, and 83.3% received R-CHOP. For double/triple expressor lymphoma patients received R-DA-EPOCH. The findings of our study demonstrated that the survival rate in both R-CHOP and R-DA-EPOCH is mostly similar. |
format | Online Article Text |
id | pubmed-8648798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-86487982021-12-17 Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. Devi, Kanta Shaikh, Muhammad Usman Ali, Natasha Bahadur Adil, Salman Naseem Khan, Maria Soomar, Salman Muhammad Leuk Res Rep Article In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multivariable cox-proportional hazard model was used to estimate the hazard ratios in patients receiving these treatment regimens considering p-value ≤0.05 significant. The survival rate among double/triple expressor lymphoma patients received R-DA-EPOCH was 82.8%, and 83.3% received R-CHOP. For double/triple expressor lymphoma patients received R-DA-EPOCH. The findings of our study demonstrated that the survival rate in both R-CHOP and R-DA-EPOCH is mostly similar. Elsevier 2021-11-29 /pmc/articles/PMC8648798/ /pubmed/34926144 http://dx.doi.org/10.1016/j.lrr.2021.100284 Text en © 2021 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Devi, Kanta Shaikh, Muhammad Usman Ali, Natasha Bahadur Adil, Salman Naseem Khan, Maria Soomar, Salman Muhammad Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title | Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title_full | Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title_fullStr | Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title_full_unstemmed | Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title_short | Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience. |
title_sort | outcomes of patients with double/triple expressor diffuse large b-cell lymphoma (dlbcl) treated with r-da-epoch/r-chop: a single-center experience. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648798/ https://www.ncbi.nlm.nih.gov/pubmed/34926144 http://dx.doi.org/10.1016/j.lrr.2021.100284 |
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