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Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

Neurologic disorders often disproportionately affect specific brain regions, and different apoptotic mechanisms may contribute to white matter pathology in leukodystrophies or gray matter pathology in poliodystrophies. We previously showed that neural progenitors that generate cerebellar gray matter...

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Detalles Bibliográficos
Autores principales:	Cleveland, Abigail H., Romero-Morales, Alejandra, Azcona, Laurent Alfonso, Herrero, Melisa, Nikolova, Viktoriya D., Moy, Sheryl, Elroy-Stein, Orna, Gama, Vivian, Gershon, Timothy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648801/ https://www.ncbi.nlm.nih.gov/pubmed/34873168 http://dx.doi.org/10.1038/s41419-021-04422-z

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