Complete Pathological Response After Neoadjuvant Short‐Course Immunotherapy with Ipilimumab and Nivolumab in Locally Advanced MSI‐H/dMMR Rectal Cancer

BACKGROUND: Patients with colorectal carcinoma and high‐grade microsatellite instability (MSI‐H) or deficiency in mismatch repair (dMMR) exceptionally respond to immune checkpoint inhibitors (ICIs). ICIs are more active in treatment‐naïve patients than in patients with refractory MSI‐H/dMMR metastat...

Descripción completa

Detalles Bibliográficos
Autores principales: Trojan, Jörg, Stintzing, Sebastian, Haase, Oliver, Koch, Christine, Ziegler, Paul, Demes, Melanie, Jelas, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Precision Medicine Clinic: Molecular Tumor Board
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649008/
https://www.ncbi.nlm.nih.gov/pubmed/34431576
http://dx.doi.org/10.1002/onco.13955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649008/
https://www.ncbi.nlm.nih.gov/pubmed/34431576
http://dx.doi.org/10.1002/onco.13955

Ejemplares similares