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Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy

BACKGROUND: The use of boluses for radiation therapy is very necessary to overcome the problem of sending inhomogeneous doses in the target volume due to irregularities on the surface of the skin. The bolus materials for radiation therapy need to be evaluated. OBJECTIVE: The present study aims to ev...

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Autores principales: Endarko, Endarko, Aisyah, Siti, Carina, Chycilia Clara Chandra, Nazara, Trimawarti, Sekartaji, Gandes, Nainggolan, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649160/
https://www.ncbi.nlm.nih.gov/pubmed/34904070
http://dx.doi.org/10.31661/jbpe.v0i0.2004-1108
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author Endarko, Endarko
Aisyah, Siti
Carina, Chycilia Clara Chandra
Nazara, Trimawarti
Sekartaji, Gandes
Nainggolan, Andreas
author_facet Endarko, Endarko
Aisyah, Siti
Carina, Chycilia Clara Chandra
Nazara, Trimawarti
Sekartaji, Gandes
Nainggolan, Andreas
author_sort Endarko, Endarko
collection PubMed
description BACKGROUND: The use of boluses for radiation therapy is very necessary to overcome the problem of sending inhomogeneous doses in the target volume due to irregularities on the surface of the skin. The bolus materials for radiation therapy need to be evaluated. OBJECTIVE: The present study aims to evaluate some handmade boluses for megavoltage electron and photon radiation therapy. Several dosimetric properties of the synthesized boluses, including relative electron density (RED), transmission factor, mass attenuation coefficient, percentage depth dose (PDD), and percentage surface dose (PSD) were investigated. MATERIAL AND METHODS: In this experimental study, we evaluated natural rubber, silicone rubber mixed either with aluminum or bismuth, paraffin wax, red plasticine, and play-doh as soft tissue equivalent. CT-simulator, in combination with ECLIPSE software, was used to determine bolus density. Meanwhile, Linear Accelerator (Linac) Clinac iX (Varian Medical Systems, Palo Alto), solid water phantom, and Farmer ionization chamber were used to measure and analyze of dosimetric properties. RESULTS: The RED result analysis has proven that all synthesized boluses are equivalent to the density of soft tissue such as fat, breast, lung, and liver. The dosimetric evaluation also shows that all synthesized boluses have a density similar to the density of water and can increase the surface dose with a value ranging from 6-20% for electron energy and 30-50% for photon energy. CONCLUSION: In general, all synthesized boluses have an excellent opportunity to be used as an alternative tissue substitute in the surface area of the body when using megavoltage electron and photon energy.
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spelling pubmed-86491602021-12-12 Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy Endarko, Endarko Aisyah, Siti Carina, Chycilia Clara Chandra Nazara, Trimawarti Sekartaji, Gandes Nainggolan, Andreas J Biomed Phys Eng Original Article BACKGROUND: The use of boluses for radiation therapy is very necessary to overcome the problem of sending inhomogeneous doses in the target volume due to irregularities on the surface of the skin. The bolus materials for radiation therapy need to be evaluated. OBJECTIVE: The present study aims to evaluate some handmade boluses for megavoltage electron and photon radiation therapy. Several dosimetric properties of the synthesized boluses, including relative electron density (RED), transmission factor, mass attenuation coefficient, percentage depth dose (PDD), and percentage surface dose (PSD) were investigated. MATERIAL AND METHODS: In this experimental study, we evaluated natural rubber, silicone rubber mixed either with aluminum or bismuth, paraffin wax, red plasticine, and play-doh as soft tissue equivalent. CT-simulator, in combination with ECLIPSE software, was used to determine bolus density. Meanwhile, Linear Accelerator (Linac) Clinac iX (Varian Medical Systems, Palo Alto), solid water phantom, and Farmer ionization chamber were used to measure and analyze of dosimetric properties. RESULTS: The RED result analysis has proven that all synthesized boluses are equivalent to the density of soft tissue such as fat, breast, lung, and liver. The dosimetric evaluation also shows that all synthesized boluses have a density similar to the density of water and can increase the surface dose with a value ranging from 6-20% for electron energy and 30-50% for photon energy. CONCLUSION: In general, all synthesized boluses have an excellent opportunity to be used as an alternative tissue substitute in the surface area of the body when using megavoltage electron and photon energy. Shiraz University of Medical Sciences 2021-12-01 /pmc/articles/PMC8649160/ /pubmed/34904070 http://dx.doi.org/10.31661/jbpe.v0i0.2004-1108 Text en Copyright: © Journal of Biomedical Physics and Engineering https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 Unported License, ( http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Endarko, Endarko
Aisyah, Siti
Carina, Chycilia Clara Chandra
Nazara, Trimawarti
Sekartaji, Gandes
Nainggolan, Andreas
Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title_full Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title_fullStr Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title_full_unstemmed Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title_short Evaluation of Dosimetric Properties of Handmade Bolus for Megavoltage Electron and Photon Radiation Therapy
title_sort evaluation of dosimetric properties of handmade bolus for megavoltage electron and photon radiation therapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649160/
https://www.ncbi.nlm.nih.gov/pubmed/34904070
http://dx.doi.org/10.31661/jbpe.v0i0.2004-1108
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