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Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine

BACKGROUND: In developing countries like India, cobalt-60 machines still find their applicability, considering the cost and maintenance issues. With a view to deliver conformal treatment plans using teletherapy machines, an automated Multi-Leaf Collimator (MLC) was developed for the existing machine...

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Autores principales: Akula, Roopa Rani, Ayyangar, Komanduri, Reddy, Alla Ramalinga, Kumar, Ayyalasomayajula Anil, Yadagiri Reddy, Pal Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649162/
https://www.ncbi.nlm.nih.gov/pubmed/34904069
http://dx.doi.org/10.31661/jbpe.v0i0.2002-1073
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author Akula, Roopa Rani
Ayyangar, Komanduri
Reddy, Alla Ramalinga
Kumar, Ayyalasomayajula Anil
Yadagiri Reddy, Pal Reddy
author_facet Akula, Roopa Rani
Ayyangar, Komanduri
Reddy, Alla Ramalinga
Kumar, Ayyalasomayajula Anil
Yadagiri Reddy, Pal Reddy
author_sort Akula, Roopa Rani
collection PubMed
description BACKGROUND: In developing countries like India, cobalt-60 machines still find their applicability, considering the cost and maintenance issues. With a view to deliver conformal treatment plans using teletherapy machines, an automated Multi-Leaf Collimator (MLC) was developed for the existing machines as a retrofit attachment to the collimator assembly without any modifications to the unit. OBJECTIVE: This study aims to investigate the radiation characteristics of leaf designs incorporated in two add-on prototype MLC systems with respect to the shape of leaf projected at the isocenter plane and the isodose distribution around the target. Besides, the dosimetric characteristics of prototype MLC with divergent leaf design are validated through simulation and experimental measurements. MATERIAL AND METHODS: In this experimental study, two add-on prototype MLC systems were designed and fabricated. The characteristic measurements of leaf designs incorporated in both the prototypes were carried out using Gafchromic films (GAF) and compared with Monte Carlo (MC) simulations. For divergent leaf design, beam profiles were obtained using Monte Carlo simulations which are complemented with the results obtained from measurements of radiochromic films and ionization chamber (IC) profiler. Dosimetric characteristics like radiation field width and beam penumbra were evaluated. RESULTS: The Monte Carlo simulated data are in agreement with experimental data from IC profiler as well as from Radiochromic films. The results of this study are well within acceptable tolerance limits. CONCLUSION: The prototype MLC system designed for existing telecobalt machines supports its clinical applicability for conformal therapy to better manage treatment in rural areas, which can provide superior cost effective treatments.
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spelling pubmed-86491622021-12-12 Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine Akula, Roopa Rani Ayyangar, Komanduri Reddy, Alla Ramalinga Kumar, Ayyalasomayajula Anil Yadagiri Reddy, Pal Reddy J Biomed Phys Eng Original Article BACKGROUND: In developing countries like India, cobalt-60 machines still find their applicability, considering the cost and maintenance issues. With a view to deliver conformal treatment plans using teletherapy machines, an automated Multi-Leaf Collimator (MLC) was developed for the existing machines as a retrofit attachment to the collimator assembly without any modifications to the unit. OBJECTIVE: This study aims to investigate the radiation characteristics of leaf designs incorporated in two add-on prototype MLC systems with respect to the shape of leaf projected at the isocenter plane and the isodose distribution around the target. Besides, the dosimetric characteristics of prototype MLC with divergent leaf design are validated through simulation and experimental measurements. MATERIAL AND METHODS: In this experimental study, two add-on prototype MLC systems were designed and fabricated. The characteristic measurements of leaf designs incorporated in both the prototypes were carried out using Gafchromic films (GAF) and compared with Monte Carlo (MC) simulations. For divergent leaf design, beam profiles were obtained using Monte Carlo simulations which are complemented with the results obtained from measurements of radiochromic films and ionization chamber (IC) profiler. Dosimetric characteristics like radiation field width and beam penumbra were evaluated. RESULTS: The Monte Carlo simulated data are in agreement with experimental data from IC profiler as well as from Radiochromic films. The results of this study are well within acceptable tolerance limits. CONCLUSION: The prototype MLC system designed for existing telecobalt machines supports its clinical applicability for conformal therapy to better manage treatment in rural areas, which can provide superior cost effective treatments. Shiraz University of Medical Sciences 2021-12-01 /pmc/articles/PMC8649162/ /pubmed/34904069 http://dx.doi.org/10.31661/jbpe.v0i0.2002-1073 Text en Copyright: © Journal of Biomedical Physics and Engineering https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 Unported License, ( http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Akula, Roopa Rani
Ayyangar, Komanduri
Reddy, Alla Ramalinga
Kumar, Ayyalasomayajula Anil
Yadagiri Reddy, Pal Reddy
Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title_full Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title_fullStr Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title_full_unstemmed Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title_short Validation of Leaf Design Characteristics of an Add-on Automated Multi Leaf Collimator for Telecobalt Therapy Machine
title_sort validation of leaf design characteristics of an add-on automated multi leaf collimator for telecobalt therapy machine
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649162/
https://www.ncbi.nlm.nih.gov/pubmed/34904069
http://dx.doi.org/10.31661/jbpe.v0i0.2002-1073
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