Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units

A series of novel palladium(II) and nickel(II) complexes of multifunctionalized aroylaminocarbo-N-thioylpyrrolinates were synthesized and characterized by analytical and spectroscopic techniques. The biological properties of the freshly prepared compounds were screened against S. aureus, B. subtilis...

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Autores principales: Poyraz, Samet, Belveren, Samet, Aydınoğlu, Sabriye, Ulger, Mahmut, de Cózar, Abel, de Gracia Retamosa, Maria, Sansano, Jose M, Döndaş, H Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649204/
https://www.ncbi.nlm.nih.gov/pubmed/34925620
http://dx.doi.org/10.3762/bjoc.17.192
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author Poyraz, Samet
Belveren, Samet
Aydınoğlu, Sabriye
Ulger, Mahmut
de Cózar, Abel
de Gracia Retamosa, Maria
Sansano, Jose M
Döndaş, H Ali
author_facet Poyraz, Samet
Belveren, Samet
Aydınoğlu, Sabriye
Ulger, Mahmut
de Cózar, Abel
de Gracia Retamosa, Maria
Sansano, Jose M
Döndaş, H Ali
author_sort Poyraz, Samet
collection PubMed
description A series of novel palladium(II) and nickel(II) complexes of multifunctionalized aroylaminocarbo-N-thioylpyrrolinates were synthesized and characterized by analytical and spectroscopic techniques. The biological properties of the freshly prepared compounds were screened against S. aureus, B. subtilis, A. hydrophila, E. coli, and A. baumannii bacteria and antituberculosis activity against M. tuberculosis H37Rv strains. Also, the antifungal activity was studied against C. albicans, C. tropicalis, and C. glabrata standard strains. A deep conformational survey was monitored using DFT calculations with the aim to explain the importance of the final conformation in the biological experimental results.
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spelling pubmed-86492042021-12-16 Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units Poyraz, Samet Belveren, Samet Aydınoğlu, Sabriye Ulger, Mahmut de Cózar, Abel de Gracia Retamosa, Maria Sansano, Jose M Döndaş, H Ali Beilstein J Org Chem Full Research Paper A series of novel palladium(II) and nickel(II) complexes of multifunctionalized aroylaminocarbo-N-thioylpyrrolinates were synthesized and characterized by analytical and spectroscopic techniques. The biological properties of the freshly prepared compounds were screened against S. aureus, B. subtilis, A. hydrophila, E. coli, and A. baumannii bacteria and antituberculosis activity against M. tuberculosis H37Rv strains. Also, the antifungal activity was studied against C. albicans, C. tropicalis, and C. glabrata standard strains. A deep conformational survey was monitored using DFT calculations with the aim to explain the importance of the final conformation in the biological experimental results. Beilstein-Institut 2021-12-02 /pmc/articles/PMC8649204/ /pubmed/34925620 http://dx.doi.org/10.3762/bjoc.17.192 Text en Copyright © 2021, Poyraz et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Full Research Paper
Poyraz, Samet
Belveren, Samet
Aydınoğlu, Sabriye
Ulger, Mahmut
de Cózar, Abel
de Gracia Retamosa, Maria
Sansano, Jose M
Döndaş, H Ali
Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title_full Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title_fullStr Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title_full_unstemmed Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title_short Biological properties and conformational studies of amphiphilic Pd(II) and Ni(II) complexes bearing functionalized aroylaminocarbo-N-thioylpyrrolinate units
title_sort biological properties and conformational studies of amphiphilic pd(ii) and ni(ii) complexes bearing functionalized aroylaminocarbo-n-thioylpyrrolinate units
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649204/
https://www.ncbi.nlm.nih.gov/pubmed/34925620
http://dx.doi.org/10.3762/bjoc.17.192
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