MutTMPredictor: Robust and accurate cascade XGBoost classifier for prediction of mutations in transmembrane proteins

Transmembrane proteins have critical biological functions and play a role in a multitude of cellular processes including cell signaling, transport of molecules and ions across membranes. Approximately 60% of transmembrane proteins are considered as drug targets. Missense mutations in such proteins c...

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Detalles Bibliográficos
Autores principales: Ge, Fang, Zhu, Yi-Heng, Xu, Jian, Muhammad, Arif, Song, Jiangning, Yu, Dong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649221/
https://www.ncbi.nlm.nih.gov/pubmed/34938415
http://dx.doi.org/10.1016/j.csbj.2021.11.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649221/
https://www.ncbi.nlm.nih.gov/pubmed/34938415
http://dx.doi.org/10.1016/j.csbj.2021.11.024

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